Results 121 to 130 of about 6,462,348 (266)

Oral Semaglutide in Routine Clinical Practice: 24‐Month Real‐World Effectiveness, Persistence and Safety in Adults With Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Real‐world long‐term data on oral semaglutide are limited. We evaluated its 24‐month effectiveness, persistence, and safety in adults with type 2 diabetes (T2D). Materials and Methods This retrospective real‐world study included 232 adults with T2D initiating oral semaglutide at an Italian diabetes clinic.
Maria Pompea Antonia Baldassarre, Giulia Di Dalmazi, Federica Carrieri, Giorgia Centorame, Luigi Piacentino, Sara Coluzzi, Gloria Formoso   +6 more
wiley   +1 more source

Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang, Kevin Cho, Max C. Petersen, Kai E. Jones, Gary J. Patti, Janet B. McGill, Samantha A. DiGruccio   +6 more
wiley   +1 more source

Supplementary Material for: Atypical central serous chorioretinopathy masquerading as Vogt-Koyanagi-Harada disease: a case report.

Introduction: We aimed to describe a clinical presentation of central serous retinopathy that poses a diagnostic and management dilemma. Case presentation: A 30-year-old male patient presented with bilateral vision loss and multifocal serous retinal ...
Choi P. (18016015), Shieh D. (18429273), Ufret-Vincenty R.L. (18429279), Duran M. (4275412), He Y.-G. (18429276)   +4 more
core   +1 more source

Diagnosis and Management of Adult Type 1 Diabetes Mellitus: Systematic Reviews of Biomarkers, Insulin Regimens and Insulin Delivery Devices Highlighting Evidence Gaps in Emergency and Humanitarian Settings

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Supporting the World Health Organization's (WHO) 2021 Global Diabetes Compact's goals, we conducted three systematic reviews on type 1 diabetes (T1D) in adults concerning (1) diagnostic biomarkers, (2) insulin regimens and (3) insulin delivery devices, focusing on emergency and humanitarian settings.
Niyati Patwa, Alexandria Bennett, Nicole Shaver, Lama Dahroug, Becky Skidmore, Shannon E. Kelly, George Wells, Andrea C. Tricco, Heather Lochnan, Julian Little, Melissa Brouwers   +10 more
wiley   +1 more source

Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel

Internal Medicine Journal, EarlyView.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorporation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) as an additional pillar of cardiorenal therapy alongside renin–angiotensin ...
Eugenia Pedagogos, Roger Chen, Adam Nelson, Sunil Badve, Roy Rasalam, Richard MacIsaac   +5 more
wiley   +1 more source

Noncoding RNAs as novel diagnostic biomarkers for diabetic retinopathy: A systematic review and meta‐analysis

Journal of Diabetes Investigation, EarlyView.
The systematic review and meta‐analysis (Embase, PubMed, and Web of Science; up to August 2025) evaluated circulating noncoding RNAs (ncRNAs) as noninvasive early diagnostic biomarkers for diabetic retinopathy (DR). From 17 articles (24 studies, 1,983 DR patients vs 1,437 controls), a random‐effects model yielded pooled sensitivity of 0.81, specificity
Ting Zhang, Donghong Xu
wiley   +1 more source

A clinical study on central serous chorioretinopathy [PDF]

, 2012
INTRODUCTION: Central serous chorioretinopathy is a disease characterized by spontaneous serous macular detachment of unknown etiology, usually self-limiting but often recurs.
Vimalkumar, N
core  

Quantitative and Qualitative Spectral Domain Optical Coherence Tomography Analysis of Subretinal Deposits in Patients with Acute Central Serous Retinopathy

, 2013
PURPOSE: To perform qualitative and quantitative analyses of subretinal protein deposits (PDs), seen in acute central serous retinopathy (CSR) patients, using high-resolution spectral domain optical coherence tomography (SD-OCT), in order to investigate ...
Rosen, Richard B, Landa, Gennady, Tai, Katy W, Barnett, Jonathan A, Garcia, Patricia M T   +4 more
core   +1 more source

Effects of esaxerenone add‐on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Makoto Ohara, Takemasa Omachi, Nobuaki Takehana, Tomoki Fujikawa, Naoya Osaka, Shunichiro Irie, Michishige Terasaki, Yusaku Mori, Takanori Matsui, Sho‐ichi Yamagishi   +9 more
wiley   +1 more source

Hepatic steatosis risk in nonobese Chinese adults with type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) may be an important comorbidity in nonobese Chinese adults with type 1 diabetes (T1D). We assessed the likelihood of hepatic steatosis using the hepatic steatosis index (HSI) in 47 nonobese Chinese adults with T1D (mean age 46.9 ± 14.1 years; BMI 22.6 ± 2.5 kg/m2) and examined ...
Zehua Jin, Jianhua Ma, Yuanyang Zhao, Yi Luo, Christopher K Rayner, Tongzhi Wu, Yong Luo   +6 more
wiley   +1 more source