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Antioxidants and Retinal Diseases [PDF]
Antioxidants, 2019 The retina is a thin membrane derived from the neuroectoderm, it is the physical morphological substrate in which the transformation of light energy into electrical impulses, that later will be led to the cerebral cortex, is performed [...]
Miranda, María +1 more
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‘Statins in retinal disease’ [PDF]
Eye, 2018 Statins are known for their blood cholesterol-lowering effect and are widely used in patients with cardiovascular and metabolic diseases. Research over the past three decades shows that statins have diverse effects on different pathophysiological pathways involved in angiogenesis, inflammation, apoptosis, and anti-oxidation, leading to new therapeutic ...
Al-Janabi, A +2 more
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Gene's hubs in retinal diseases: A retinal disease network [PDF]
Heliyon, 2018 Retinal diseases associated with the dysfunction or death of photoreceptors are a major cause of blindness around the world, improvements in genetics tools, like next generation sequencing (NGS) allows the discovery of genes and genetic changes that lead to many of those retinal diseases.
J.M. Lázaro-Guevara +7 more
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Retinal blood vessels extraction using probabilistic modelling [PDF]
, 2014 © 2014 Kaba et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
A Hoover +22 more
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International Journal of Molecular Sciences, 2022 Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of diseases that cause vision loss due to abnormal development or due to the dysfunction or degeneration of the photoreceptors or the retinal pigment epithelium [...]
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Retinal imaging in inherited retinal diseases
Annals of Eye Science, 2020 Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population. The advances in ocular genetics, retinal imaging and molecular biology, have conspired to create the ideal environment for establishing treatments for IRD, with the first approved gene therapy and the commencement of multiple therapy trials.
Georgiou, Michalis +2 more
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Normative Data and Minimally Detectable Change for Inner Retinal Layer Thicknesses Using a Semi-automated OCT Image Segmentation Pipeline [PDF]
, 2019 Neurodegenerative and neuroinflammatory diseases regularly cause optic nerve and retinal damage. Evaluating retinal changes using optical coherence tomography (OCT) in diseases like multiple sclerosis has thus become increasingly relevant.
Asseyer, Susanna +9 more
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Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
, 2017 Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
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Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. [PDF]
, 2017 The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could ...
Angueyra, Juan M +9 more
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Factors Associated With Retinal Vessel Diameters in an Elderly Population: the Thessaloniki Eye Study [PDF]
, 2019 Purpose: To identify the factors associated with retinal vessel diameters in the population of the Thessaloniki Eye Study. Methods: Cross-sectional population-based study (age ≥ 60 years). Subjects with glaucoma, late age-related macular degeneration,
Anastasopoulos, Eleftherios +9 more
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