Results 21 to 30 of about 2,469,822 (264)

Stem cell-based therapeutic applications in retinal degenerative diseases [PDF]

, 2010
Retinal degenerative diseases that target photoreceptors or the adjacent retinal pigment epithelium (RPE) affect millions of people worldwide. Retinal degeneration (RD) is found in many different forms of retinal diseases including retinitis pigmentosa ...
Suzanne T Ildstad, Enzmann, Volker, Yiming Huang, Volker Enzmann, Huang, Yiming, Ildstad, Suzanne T, Suzanne T. Ildstad   +6 more
core   +2 more sources

Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

Journal of Lipid Research, 2010
This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be present in high amounts in oxidized LDL deposits associated with atheromatous plaques.
Ignacio R. Rodríguez, Ignacio M. Larrayoz   +1 more
doaj   +1 more source

When HIV Immunodeficiency and Heterochromia Confuse the Issue: Recurrent Zoster Uveitis Mistaken for Fuchs’ Uveitis

Journal of Ophthalmic & Vision Research, 2021
Purpose: We report a case with iris heterochromia misdiagnosed as Fuchs' uveitis which finally turned out to be a unilateral zoster uveitis in an HIV-positive patient.
Ioannis Papasavvas, Bruno Jeannin, Carle Pierre Herbort   +2 more
doaj   +1 more source

Preoperative Steroid Use in Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment after 23-Gauge Vitrectomy

Journal of Ophthalmology, 2020
Background. Rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) is rare and the prognosis is poor. This retrospective study evaluated the effect of preoperative steroid on the clinical outcome of patients with RRDCD receiving ...
Jianhua Wu, Rui Zhang, Junwen He, Changzhong Xu, Zhaohui Li   +4 more
doaj   +1 more source

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation [PDF]

, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632), Jennifer Scott, Heather Thomson, Xiaoli Chen, Lotery, Andrew J., Xiaoli Chen (102563), Cooke, J.J., Scott, Jennifer A., Andrew Lotery, Heather Thomson (637631), Thomson, Heather, Jessica Cooke, Parwez Hossain, Jennifer Scott (637633), Chen, Xiaoli, Hossain, Parwez, Andrew Lotery (637635), Parwez Hossain (637634)   +17 more
core   +1 more source

Clinicopathology of non-infectious choroiditis: evolution of its appraisal during the last 2–3 decades from “white dot syndromes” to precise classification

Journal of Ophthalmic Inflammation and Infection, 2021
Choroidal imaging investigation techniques were very limited until 2–3 decades ago. Fluorescein angiography (FA) was not suited for the analysis of the choroidal compartment and B-scan ultrasonography did not provide enough accuracy.
Carl P. Herbort, Piergiorgio Neri, Ioannis Papasavvas   +2 more
doaj   +1 more source

Stem Cell Treatment in Retinal Diseases: Recent Developments

, 2018
Stem cells are undifferentiated cells which have the ability to self-renew and differentiate into mature cells. They are highly proliferative, implying that an unlimited number of mature cells can be generated from a given stem cell source. On this basis,
ÖNER, Ayşe, Ayşe Öner
core   +1 more source

Complement activation in retinal degeneration

, 2016
Our aim is to investigate a common role of the complement system in the pathogenesis of retinal disease, by assessing the expression profile of complement component 3 (C3) in three mechanistically distinct models of retinal degeneration: light-damage ...
Provis, Jan, Valter (Valter-Kocsi), Krisztina, Natoli, Riccardo, Rutar, Matthew   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Vogt-Koyanagi-Harada disease is always bilateral: reports of unilateral cases failed to use choroidal investigations showing subclinical involvement of the fellow eye

Journal of Ophthalmic Inflammation and Infection, 2021
Background/purpose Vogt-Koyanagi-Harada (VKH) disease is a primary stromal choroiditis and a bilateral granulomatous panuveitis which, if not treated early and properly, could have a deleterious evolution. The purpose of our case report is to demonstrate
Ioannis Papasavvas, Carl P. Herbort
doaj   +1 more source