Results 11 to 20 of about 301,242 (246)

Retinal Disease and Metabolism [PDF]

open access: yesLife, 2022
Retinal diseases, such as diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinopathy of prematurity (ROP), are some of the leading causes of blindness all over the world [...]
Zhongjie Fu   +3 more
openaire   +3 more sources

Retinal prostheses in degenerative retinal diseases

open access: yesJournal of the Chinese Medical Association, 2015
Degenerative retinal diseases may lead to significant loss of vision. Age-related macular degeneration (AMD) and retinitis pigmentosa (RP), which eventually affect the photoreceptors, are the two most common retinal degenerative diseases. Once the photoreceptorcells are lost, there are no known effective therapies for AMD or RP.
Lin, Tai-Chi   +6 more
openaire   +2 more sources

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

open access: yes, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick   +2 more
core   +1 more source

Microperimetry in Retinal Diseases

open access: yesAsia-Pacific Journal of Ophthalmology, 2023
Retinal microperimetry (MP) is a procedure that assesses the retinal sensitivity while the fundus is directly observed, and an eye tracker system is active to compensate for involuntary eye movements during testing. With this system, the sensitivity of a small locus can be accurately determined, and it has become an established ophthalmic test for ...
Shintaro, Horie   +8 more
openaire   +2 more sources

Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]

open access: yes, 2012
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
A Lux   +68 more
core   +2 more sources

Diagnosis of Inherited Retinal Diseases [PDF]

open access: yesKlinische Monatsblätter für Augenheilkunde, 2021
AbstractInherited retinal diseases are a frequent cause of severe visual impairment or blindness in children and adults of working age. Across this group of diseases, there is great variability in the degree of visual impairment, the impact on everyday life, disease progression, and the suitability to therapeutic intervention.
Johannes Birtel   +4 more
openaire   +3 more sources

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Inflammation in Retinal Disease [PDF]

open access: yesInternational Journal of Inflammation, 2013
Ocular inflammation and its related complications are important causes of vision loss. Inflammatory processes have long been implicated in the pathogenesis and sequelae of noninfectious uveitis and understood to underlie the macular edema which may arise following even uncomplicated intraocular surgeries [1].
Scott M. Whitcup   +3 more
openaire   +3 more sources

Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy [PDF]

open access: yes, 2016
PURPOSE To characterize outer retina structure in best vitelliform macular dystrophy (BVMD) and to determine the effect of macular lesions on overlying and adjacent photoreceptors.
Carroll, Joseph   +7 more
core   +2 more sources

Autoimmune and autoinflammatory mechanisms in uveitis [PDF]

open access: yes, 2014
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
A Amadi-Obi   +203 more
core   +1 more source

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