Results 71 to 80 of about 33,995 (273)

Analysis of microorganisms and antibiotic resistance in medical instruments in the central sterile supply department (CSSD) of hospitals before and after sterilization [PDF]

Sterilization is essential in preventing the spread of pathogenic bacteria and antibiotic resistance in hospital settings. This study examines the microbial growth and antibiotic resistance of seven medical instruments from the Central Supply Sterile ...
Woro Hapsari, Sajidan, Suranto, Nur Hafidha Hikmayani   +3 more
core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Practice of quality management for dental handpiece processing based on FOCUS-PDCA programme

BMC Oral Health
Objective This study applies the find, organise, clarify, understand, select – plan, do, check and act (FOCUS-PDCA) programme to analyse factors affecting dental handpiece (DHP) processing quality and to optimise the workflow using this quality ...
Feng-lian Che, Jia-qi Li, Shuang-di Li, Kan-wen Ji, Ming-zhi Jin, Li-ming Qian   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Prevalence and Risk Factors of Work-Related Musculoskeletal Disorders in Central Sterile Supply Technicians, Nakhon Si Thammarat Province, Thailand

Journal of Health Science and Medical Research (JHSMR)
Objective: The study aimed to examine the prevalence of work-related musculoskeletal disorders among central sterile supply technicians (CSSTs) in Nakhon Si Thammarat Province, Thailand, and investigate the risk factors associated with these disorders ...
Withaya Chanchai, Ratree Nacglud, Keatkongkrai​ Bunnum, Nureeya Promsorn, Laddawan Duangmusik, Warunee Suwanrat, Wichuda Chantasin, Kritsana Thonnan   +7 more
doaj   +1 more source

IDENTIFIKASI BAKTERI PADA RUANG CSSD (CENTRAL STERILE SUPPLY DEPARTMENT) RSU UNDATA PALU TAHUN 2016

, 2017
ABSTRAK Latar belakang. Rumah sakit adalah sarana kesehatan yang menyelenggarakan pelayanan kesehatan perorangan secara paripurna dengan menyediakan pelayanan rawat inap, rawat jalan dan gawat darurat.
AMALIA MEGA PUTRI MUJUR N 101 12 161
core  

STROBE checklist for "Assess the workload management model and enhanced quality control in the Central Sterile Supply Department: A Study Protocol

STROBE checklist for "Assess the workload management model and enhanced quality control in the Central Sterile Supply Department: A Study Protocol.
Prachi Supare (18409275)
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Refined management in risk control of extrahepatic laparoscopic instrument handover

Sterile Supply
ObjectiveThe present study intends to analyze and explore the application effect of the refined management in risk control of extrahepatic laparoscopic instrument handover.MethodsA retrospective analysis of 1,973 adverse events during extrahepatic ...
Tianqiang Zhang, Xuanxuan Huang, Caihui Yang, Zhenguang Wang, Li Fu   +4 more
doaj   +1 more source