Results 81 to 90 of about 200,011 (267)

Critical Node Control Combined with a Fully Automatic Dental Cleaning Machine for Cleaning and Disinfection of Dental Handpieces

Sterile Supply
ObjectiveThis study aims to evaluate the effectiveness of critical node control management based on the “structure-process-outcome” quality evaluation indicators combined with a fully automatic cleaning and disinfecting machine for the cleaning and ...
Xiuhui Wu, Xiaohe Xu, Fenglan Zhang, Qing Ruan, Ying Li   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Theoretical and experimental study on the cooling time of a single device after sterilization based on a zero-dimensional heat transfer model

Open Medicine
To establish a zero-dimensional heat-transfer model for an isolated single-sealed 316 stainless-steel cylindrical device after pressure-steam sterilization and to evaluate whether the 30-min cooling time required by national standards provides an ...
Liu Zhili, Yang Haiyi, Chen Xiaoxuan, Ye Huamei, Wang Yuewei   +4 more
doaj   +1 more source

Research integrity and data ethics in AI-driven integrated healthcare: a critical appraisal

Frontiers in Public Health
The convergence of artificial intelligence (AI) and healthcare is reshaping clinical practice, yet this transformation raises pressing questions about scientific rigor and ethical responsibility.
Wei Zeng, Hong Wei, Yongkai Chen, Jing Tang, Jingyi Ge, Huilong Chen   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Genome of a novel Fangshan bunya-like virus identified in mosquitoes from Shandong Province, China

Scientific Reports
Mosquitoes are important vectors of a wide range of viruses and serve as pivotal vectors with complex ecological functions that facilitate the transmission of these pathogens between hosts, such as humans, through biting behavior.
Yuli Zhang, Yujie Liu, Lin Liu, Yingxin Tu, Meixi Ren, Guoyu Niu, Hengyi Sun, Yujing Zhu   +7 more
doaj   +1 more source

Improving precision instrument cleaning with a quality control module: implementation and outcomes

Frontiers in Public Health
ObjectiveTo evaluate the effectiveness of a cleaning quality control module integrated into a hospital’s Disinfection Supply Center (DSC) for improving the cleaning quality of precision surgical instruments.MethodsIn June 2023, a cleaning quality control
Juan Xiong, Juan Xiong, Wei Jiang, Wei Wan, Li Zuo, Ping Tu, Dong Xia Rao   +6 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Control spending in hospital supplies of common use in Central Hospital

, 2015
This essay arises from the need to determine how to improve the existing tools to quantify the actual expenditure of the elements commonly used in hospital Central. The elements of common hospital use as the name suggests are commonly used in the institution and are required for normal operation of the hospital, these hospitals are established elements
openaire   +1 more source