Results 101 to 110 of about 194,778 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Local Anesthesia-Based Modified Cartilage “Inlay” Graft Myringoplasty for Repairing Large Perforation

Ear, Nose & Throat Journal
Objective: The objective of this study was to evaluate the graft success rate and hearing outcome of modified cartilage inlay graft technique for repairing large perforations under local anesthesia. Study Design: Prospective case series.
Meixia Wu MD, Zhengcai Lou MD
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimising perioperative antimicrobial stewardship for Class I incisions: a clinical pharmacist-led multidisciplinary intervention and outcomes

Frontiers in Cellular and Infection Microbiology
BackgroundAppropriate prophylactic antimicrobial use in Class I (clean) incision surgery is crucial for patient safety and combating resistance. Although guidelines discourage routine prophylaxis, overuse remains prevalent.
Hui Liu, Yanli Ning, Qing Shao
doaj   +1 more source

Continuity of medication information transfer and continuous medication supply during hospital-to-home transitions - nationwide surveys in hospital and community pharmacies after implementing new legal requirements in Germany

Background While successful information transfer and seamless medication supply are fundamental to medication safety during hospital-to-home transitions, disruptions are frequently reported.
Metzger, Nadine, Seidling, Hanna M., Klasing, Sophia, Dörje, Frank, Richling, Ina, Hilgarth, Heike   +5 more
core   +1 more source

PERSONAL PROTECTIVE EQUIPMENT UTILIZATION IN CENTRAL STERILE SUPPLY DEPARTEMENT PKU MUHAMMADIYAH HOSPITAL SURAKARTA [PDF]

, 2019
Personal Protective Equipment (PPE) utilization are very effective in minimizing injuries and accident for healthcare workers. Due to high availability of potential hazard in Central Sterile Supply Departement (CSSD) PKU Muhammadiyah Surakarta hospital ...
Dewi, Etika Marsita
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Waiting times and socioeconomic status. Evidence from Norway [PDF]

We investigate whether socioeconomic status, measured by income and education, affects waiting time when controls for severity and hospital specific conditions are included.
Carlsen, Fredrik, Kaarbøe, Oddvar Martin   +1 more
core  

The Purpose and Siting of Consultant Outpatient Sessions Interim Report [PDF]

, 1974
The current provision of dietary services in the community and the demands falling on dietitians working in the community was studied by means of postal questionnaires to all medical officers of health of local health authorities, secretaries to hospital
Sheridan James, K.
core  

Organização do trabalho na unidade centro de material Central supply unit: organizing aspects

, 1998
Este trabalho aborda a Unidade Centro de Material no contexto hospitalar, e os seus aspectos organizacionais, relacionados ao dimensionamento, zoneamento, recursos materiais e humanos.This study presents the central supply unit in the hospital taking ...
Arlete Silva, Silva, Arlete
core   +1 more source