Results 31 to 40 of about 8,628 (221)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Central-Variant Posterior Reversible Encephalopathy Syndrome with Albuminocytologic Dissociation [PDF]
Case Reports in Neurology, 2018 Posterior reversible encephalopathy syndrome (PRES) is a disorder of reversible vasogenic brain edema which mainly involves the parieto-occipital lobes in various clinical settings. The main mechanism is known to be cerebral autoregulation failure and endothelial dysfunction leading to the disruption of the blood-brain barrier.
Sang-Woo Lee, Seung-Jae Lee
openaire +3 more sources
40 notas sobre la sociedad de riesgo, fase senil del capitalismo [PDF]
, 2002 Si la sociedad del riesgo es la fase senil del capitalismo, entonces la comprensión de los peligros medioambientales que se autoincrementan como una coacción del espacio social (que se puede relacionar con la necesidad de la producción de extraer ...
Hernàndez i Dobon, Francesc Jesús
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Assemblages in societies of control [PDF]
, 2018 El objetivo de este artículo es presentar las principales tesis detrás de la teoría de Gilles Deleuze y Félix Guattari sobre la aparición de las formaciones sociales de control y sobre los agenciamientos que a ellas corresponden.
Sebastián Rossi, Luis
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Obtención de biodiesel a partir de grasa bovina [PDF]
, 2008 En este trabajo se estudia específicamente la reacción de esterificación de los ácidos grasos saturados de bajo valor comercial con alcoholes de cadena corta, como el metanol anhidro al 95% y metanol comercial para la elaboración de biodiesel.
Arévalo, Pablo
core