Results 31 to 40 of about 8,976 (287)
Investigaciones e investigadores de la UAM [PDF]
, 2017 Continuamos en este número de la revista con la sección: Investigaciones en la Universidad Autónoma de Madrid, con la que se pretende dar a conocer investigaciones relacionadas con diversas disciplinas científicas que se han desarrollado o se están ...
del Peso, Luis +4 more
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Reversal of Central Sleep Apnea following Discontinuation of Opioids [PDF]
Journal of Clinical Sleep Medicine, 2012 This case report including polysomnography shows reversal of central sleep apnea after opioid withdrawal. A patient using opioids for pain was diagnosed with central sleep apnea (CSA), but was not compliant with therapy. Five years later he underwent detoxification. Subsequent polysomnography showed no sleep disordered breathing.
Matthew J, Davis +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Tecnociencias, Interdisciplina y capitalismo complejo con perspectiva latinoamericana: Pablo González Casanova [PDF]
, 2016 Presentamos el pensamiento de Pablo González Casanova (México-1922) acerca de las tecnociencias (2004) en su propuesta de una teoría crítica compleja que echa mano de los saberes de las ciencias de la complejidad de Ilya Prigogine e Isabel Stengers (1983)
Fischetti, Natalia Beatriz
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Polymeric properties of κ-carrageenan chains at diferents temperatures [PDF]
, 2010 Este trabajo describe la dependencia con la temperatura de la longitud de persistencia y el cociente característico de cadenas del polisacárido iónico κ-carragenano.
Benegas, Julio Ciro +6 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source