Results 71 to 80 of about 890,525 (317)
Services informatiques et centralités métropolitaines en région parisienne
Belgeo, 2003 The diffusion of software services reveals new centralities inside a complicated metropolitan area. Classic evolutions toward polycentrality and high territory contrasts are increasing.
Jacques Fache
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Central venous line–related thrombosis in children: association with central venous line location and insertion technique [PDF]
, 2003 Christoph Male +6 more
openalex +1 more source
Journal of Computational Geometry, 2015 An important task in trajectory analysis is clustering. The results of a clustering are often summarized by a single representative trajectory and an associated size of each cluster. We study the problem of computing a suitable representative of a set of similar trajectories.
van Kreveld, M.J. +2 more
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Port Competition and Network Polarization in the East Asian Maritime Corridor
Territoire en Mouvement, 2011 Port competition is often analyzed based on individual characteristics of seaports rather than inter-port connections. A maritime network perspective is applied to the circulation of liner vessels between East Asian ports in order to reveal their ...
César Ducruet +2 more
doaj +1 more source
Mass fall-back and accretion in the central engine of gamma-ray bursts [PDF]
, 2008 Pawan Kumar +2 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source