Results 81 to 90 of about 263,474 (283)

Sinkless: A Preliminary Study of Stress Propagation in Group Project Social Networks using a Variant of the Abelian Sandpile Model [PDF]

, 2013
We perform social network analysis on 53 students split over three semesters and 13 groups, using conventional measures like eigenvector centrality, betweeness centrality, and degree centrality, as well as defining a variant of the Abelian Sandpile Model
Knowles, Bryan, Yang, Rong
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Maximal-entropy random walk unifies centrality measures

, 2012
In this paper analogies between different (dis)similarity matrices are derived. These matrices, which are connected to path enumeration and random walks, are used in community detection methods or in computation of centrality measures for complex ...
C. M. Grinstead, D. Harel, J. G. Kemeny, J. J. Hunter, J. K. Ochab, S. Wasserman, S. White, Z. Burda   +7 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The impact of partially missing communities~on the reliability of centrality measures

, 2017
Network data is usually not error-free, and the absence of some nodes is a very common type of measurement error. Studies have shown that the reliability of centrality measures is severely affected by missing nodes.
A Rezvanian, CL Staudt, CL Staudt, D Koschützki, DJ Wang, E Costenbader, G Kossinets, JA Smith, JM Bolland, LC Freeman, LC Freeman, M Girvan, MG Kendall, P Boldi, P Bonacich, P Erdös, PJ Kim, Q Niu, S Boccaletti, S Brin, S Fortunato, S Fortunato, S Fortunato, S Wasserman, SP Borgatti, TL Frantz, TW Valente   +26 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Social networks: Prestige, centrality, and influence (Invited paper) [PDF]

We deliver a short overview of di erent centrality measures and influence concepts in social networks, and present the relation-algebraic approach to the concepts of power and influence. First, we briefly discuss four kinds of measures of centrality: the
Agnieszka Rusinowska, Harrie De Swart, Michel Grabisch, Rudolf Berghammer   +3 more
core  

Measuring centrality by a generalization of degree

, 2016
Network analysis has emerged as a key technique in communication studies, economics, geography, history and sociology, among others. A fundamental issue is how to identify key nodes, for which purpose a number of centrality measures have been developed ...
Csató, László
core   +1 more source