Results 61 to 70 of about 578,628 (285)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Discovering latent node Information by graph attention network
Scientific Reports, 2021 In this paper, we propose graph attention based network representation (GANR) which utilizes the graph attention architecture and takes graph structure as the supervised learning information.
Weiwei Gu +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Display Models for Visualization [PDF]
, 1999 Models for visualization are important, helping the developer and user to understand the visualization process; to follow the connections and the data paths through the system; and to reference and compare the functionality and the limitations of ...
Roberts, J.C.
core +1 more source
Code4Lib Journal, 2012 Semantic web representations of data are by definition graphs, and these graphs can be explored using concepts from graph theory. This paper demonstrates how semantically mapped bibliographic metadata, combined with a lightweight software architecture ...
James Powell +4 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Understanding Visualization: A formal approach using category theory and semiotics [PDF]
, 2013 This article combines the vocabulary of semiotics and category theory to provide a formal analysis of visualization. It shows how familiar processes of visualization fit the semiotic frameworks of both Saussure and Peirce, and extends these structures ...
Vickers, Paul +2 more
core +1 more source
Mapping the Intellectual Structure of COVID-19 Scientific Articles in Iran: A Scientometrics Study [PDF]
پژوهشنامه علم سنجیPurpose: The outbreak of COVID-19 in Wuhan, China, and its rapid spread to many countries worldwide has prompted numerous studies on various aspects of the disease, both internationally and within Iran.
Ismael Mostafavi +2 more
doaj +1 more source