Results 41 to 50 of about 186,598 (292)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Enlargement versus Deepening: The Trade-off Facing Economic Unions [PDF]

open access: yes
This paper analyzes the relationship between the size of an economic union and the degree of policy centralization. We consider a political economy setting in which elected representatives bargain about the degree of centralization within the union.
Gerald Willmann, Oliver Lorz
core   +3 more sources

How do basin committees deal with water crises? Reflections for adaptive water governance from South America

open access: yesEcology and Society, 2022
Adaptive water governance involves collaboration among multiple actors, social learning, and flexibility to deal with shocks and surprises. Crises thus become a useful context to assess how the institutional arrangements contribute to adaptation. However,
Micaela Trimble   +16 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Amalgamating Provincial Health Authorities

open access: yesHealth Reform Observer - Observatoire des Réformes de Santé, 2019
Reflecting the shift away from regionalized health governance in Canada's provinces, the Nova Scotia government consolidated its nine Distinct Health Authorities into the single Nova Scotia Health Authority as of 1 April 2015.
Katherine Fierlbeck
doaj  

A Mídia tem futuro?

open access: yesMatrizes, 2011
As práticas midiáticas foram confi guradas como um modelo determinado, o um-paramuitos, que o paradigma da comunicação de massa pareceu automático. O paradigma resume-se no termo inglês “the media” ? “a mídia”.
Nick Couldry
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

CENTRALISATION OR PERIPHERLISATION? A ‘NEW DEAL” IN URBAN-RURAL RELATIONS [PDF]

open access: yesStudia Universitatis Babeş-Bolyai: Geographia, 2015
Centralisation or Peripheralization? A ‘New Deal’ in Urban-Rural Relations. Beginning with the new century a new concept of regional planning has established itself in Europe, being strongly related to long-term development, especially in post-industrial
IBOLYA TÖRÖK
doaj  

THE TENDENCY TOWARDS CENTRALIZATION EXPERIENCED IN THE MANAGEMENT OF METROPOLITAN MUNICIPALITIES IN TURKEY

open access: yesMehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2021
Compared to the past, the subsidiarity principle has become more apparent with the implementation of the Metropolitan Municipality Law No. 5216 in 2004 and the Municipality Law No. 5393 in 2005.
Orhan Veli Alıcı
doaj   +1 more source

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