Results 91 to 100 of about 91,948 (288)

Critique and System: Early and Late Natorp’s Philosophy

open access: yesRUDN Journal of Philosophy
This paper presents an interpretation of the connection between Natorp’s early and late philosophy. An analysis of two versions of Natorp’s deduction of categories shows the consistent development of Natorp’s thought.
Hernán Pringe
doaj   +1 more source

Pour un modèle centre-périphérie dans les sciences sociales

open access: yesRevue d'anthropologie des connaissances, 2010
This paper deals with global hierarchies and inequalities in the production and diffusion of sociological knowledge in a North-South perspective. A centre-periphery-model is proposed in order to apprehend these inequalities.
Wiebke Keim
doaj   +1 more source

Centre – Periphery Relations Through the Trans-European Motorway in Turkey [PDF]

open access: yes
European Spatial Development Perspective aims to decentralise the congestion from the centre of Europe to peripheral countries, by supporting development through urban corridors.
Mete Başar Baypinar
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Integral assessment of urban conglomeration versus centre-periphery maglev rail systems under market imperfections [PDF]

open access: yes, 2002
New transport infrastructure has a myriad of short and long run effects. The effects on population and economic activity are most difficult to estimate. This paper introduces three different models to estimate the impacts of new infrastructure on labour ...
Elhorst, J. Paul   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

An Account of Geographic Concentration Patterns in Europe [PDF]

open access: yes
Using entropy indices and associated bootstrap tests, we describe the distribution of economic sectors across Western European regions over the 1975-2000 period. We decompose geographic concentration into its within-country and between-country components.
Marius BRÜLHART, Rolf TRAEGER
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Image‐guided metabolomics and transcriptomics reveal tumour heterogeneity in luminal A and B human breast cancer beyond glucose tracer uptake

open access: yesClinical and Translational Medicine
Background Breast cancer is a metabolically heterogeneous disease, and although the concept of heterogeneous cancer metabolism is known, its precise role in human breast cancer is yet to be fully elucidated.
Qianlu Yang   +16 more
doaj   +1 more source

Islands of islands: responses to the centre-periphery fractal model in East Futuna (Wallis and Futuna) and the Belep Islands (New Caledonia)

open access: yesIsland Studies Journal, 2018
Starting from two case studies, the Belep Islands (New Caledonia) and Futuna (Wallis and Futuna), this essay presents the hypothesis that colonial and post-colonial dynamics tend to reproduce, as in fractals, the centre-periphery model.
Adriano Favole, Lara Giordana
doaj   +1 more source

Home - About - Disclaimer - Privacy