Results 91 to 100 of about 91,948 (288)
Critique and System: Early and Late Natorp’s Philosophy
This paper presents an interpretation of the connection between Natorp’s early and late philosophy. An analysis of two versions of Natorp’s deduction of categories shows the consistent development of Natorp’s thought.
Hernán Pringe
doaj +1 more source
Pour un modèle centre-périphérie dans les sciences sociales
This paper deals with global hierarchies and inequalities in the production and diffusion of sociological knowledge in a North-South perspective. A centre-periphery-model is proposed in order to apprehend these inequalities.
Wiebke Keim
doaj +1 more source
Centre – Periphery Relations Through the Trans-European Motorway in Turkey [PDF]
European Spatial Development Perspective aims to decentralise the congestion from the centre of Europe to peripheral countries, by supporting development through urban corridors.
Mete Başar Baypinar
core
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Integral assessment of urban conglomeration versus centre-periphery maglev rail systems under market imperfections [PDF]
New transport infrastructure has a myriad of short and long run effects. The effects on population and economic activity are most difficult to estimate. This paper introduces three different models to estimate the impacts of new infrastructure on labour ...
Elhorst, J. Paul +2 more
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Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
An Account of Geographic Concentration Patterns in Europe [PDF]
Using entropy indices and associated bootstrap tests, we describe the distribution of economic sectors across Western European regions over the 1975-2000 period. We decompose geographic concentration into its within-country and between-country components.
Marius BRÜLHART, Rolf TRAEGER
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Background Breast cancer is a metabolically heterogeneous disease, and although the concept of heterogeneous cancer metabolism is known, its precise role in human breast cancer is yet to be fully elucidated.
Qianlu Yang +16 more
doaj +1 more source
Starting from two case studies, the Belep Islands (New Caledonia) and Futuna (Wallis and Futuna), this essay presents the hypothesis that colonial and post-colonial dynamics tend to reproduce, as in fractals, the centre-periphery model.
Adriano Favole, Lara Giordana
doaj +1 more source

