Results 101 to 110 of about 93,365 (307)
Clinical and Translational MedicineBackground Breast cancer is a metabolically heterogeneous disease, and although the concept of heterogeneous cancer metabolism is known, its precise role in human breast cancer is yet to be fully elucidated.
Qianlu Yang +16 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Central places versus networks: the future of collective farms built community infrastructure in Estonia [PDF]
The aim of this paper will be to discuss possibilities to shift from a central-place theory towards to a network paradigm in local and regional planning practices.
Kikas, Tavo +3 more
core
Economies of signs in writing for academic publication: the case of English Medium “National” Journals [PDF]
, 2012 The centrality of publishing in academic journals to academic knowledge work globally is largely taken as a given. Publishing is a defining aspect of scholars’ labour in the academic world, tied to both current and possible future material conditions in ...
Lillis, Theresa
core
Bolshevizing communist parties: The Algerian and South African experiences [PDF]
, 2003 In 1924 and 1925 the Comintern introduced its policy of Bolshevization. A goal of Bolshevization was the creation of mass-based communist parties.
Drew, A.
core +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
An Interdyscyplinary Model of Centre-Periphery Relations: A Theoretical Proposition
Studia Regionalne i Lokalne, 2007 The paper proposes a model in which centre-periphery relations defined at a high level of generality (from the global level down to regional structures) can be analysed from a perspective of a number of disciplines, including political science (e.g ...
Tomasz Zarycki
doaj
Espaces méditerranéens, vers une convergence politique et économique ? [PDF]
, 2010 Do political and commercial links between EUROMED member states tend to increase during the last decade? Tools from ‘Social Network Analysis' allow focusing on actors' relational structures and highlight the persistence of a centre-periphery organization
Beauguitte, Laurent, Ben Rebah, Maher
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source