Results 121 to 130 of about 93,365 (307)

Chipkin makes sense of Jo'burg's complex Vision [PDF]

open access: yes, 2013
This article gives critical praise to the published work of architect & architectural historian Clive Chipkin on Johannesburg, arguing that his embedded position allows for an intimate portrait of the city and the complexities involved in the making and ...
Lagae, Johan
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The regional impact of the single currency [PDF]

open access: yes
The essential feature of a monetary union is the irrevocable fixing of nominal exchange rates of participating countries? currencies. Regions, as sub-units of Member States, will not be directly affected by such a decision since they have - by definition
Martin Hallet
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Centre-Periphery and Specialization in the E. U.: An Analysis From a New Economic Geography Perspective [PDF]

open access: yes, 2006
This paper attempts an assessment of a number of basic statistical indicators of EU regions and countries from a New Economic Geography (NEG) perspective.
Caraveli, Helen, Darzentas, John
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Utopian semiospheres: Isolation and dialogue across borders

open access: yesSign Systems Studies
The paper applies Juri Lotman’s theory of the semiosphere to utopian studies with the aim of identifying the principal components and mode of functioning of classic utopian discourse.
Artur Blaim, Ludmiła Gruszewska-Blaim
doaj   +1 more source

Divisions of the world according to flows and networks [PDF]

open access: yes, 2011
This EuroBroadMap working paper presents the synthesis obtained by the work package Flows and Networks. Starting from several matrices describing the international system at different periods and from different perspectives (economical, political ...
Grasland, Claude, van Hamme, Gilles
core   +2 more sources

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