Results 91 to 100 of about 9,755,981 (243)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Clinical and Translational MedicineBackground Breast cancer is a metabolically heterogeneous disease, and although the concept of heterogeneous cancer metabolism is known, its precise role in human breast cancer is yet to be fully elucidated.
Qianlu Yang +16 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
An Interdyscyplinary Model of Centre-Periphery Relations: A Theoretical Proposition
Studia Regionalne i Lokalne, 2007 The paper proposes a model in which centre-periphery relations defined at a high level of generality (from the global level down to regional structures) can be analysed from a perspective of a number of disciplines, including political science (e.g ...
Tomasz Zarycki
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Language Contact: Centre and Periphery
, 2019 <p>This talk explores the concepts of centripetal and centrifugal convergence in Bantu, whereby language contact in the centre of the Bantu-speaking area leads to increased similarity of the Bantu languages involved, but language contact at ...
Marten, Lutz (7137587), Marten, Lutz
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
The core-periphery model with three regions [PDF]
We study a 3-region core-periphery model à la Krugman and compare our results with those of the standard 2-region model. The conditions for the stability of the dispersion and concentration configurations are established.
Joao Correia-da-Silva +2 more
core
Redefining Periphery: Offshore Finance, Peripheral States and the World Economy [PDF]
, 2012 Το άρθρο αυτό επιχειρεί να εξετάσει την μεταβαλλόμενη δυναμική της σχέσης μεταξύ της περιφέρειας και του κέντρου της παγκόσμιας οικονομίας. Τις τελευταίες δεκαετίες, μικρά κράτη της περιφέρειας έχουν αναλάβει έναν ολοένα και πιο σημαίνοντα ρόλο στην ...
Katsikas, Dimitris
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source