Results 201 to 210 of about 4,708,577 (333)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Correction: Clinical outcomes of fibrin glue assisted hemostasis in persistent intraoperative optic disc bleeding. [PDF]

Int J Retina Vitreous
Hansraj S, Mb T, Takkar B, Dave VP, Narula R, Ramamurthy SR, Tyagi M.   +6 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Evaluating the potential for sperm DNA fragmentation testing to guide the use of ICSI for couples with non-severe male infertility. [PDF]

Hum Reprod Open
Wang Y, Wang R, Lian Y, Yang R, Gao J, Liu J, Tang L, Liang X, Cao Y, Li W, Jin L, Zhu Y, Zhao J, Hao G, Wang H, Mol BW, Li R, Qiao J.   +17 more
europepmc   +1 more source

Palaquium rubiginosum: World Conservation Monitoring Centre

, 1998
IUCN
openalex   +1 more source

Shared decision making: really putting patients at the centre of healthcare

British medical journal, 2012
A. Stiggelbout, T. Weijden, M. Wit, D. Frosch, F. Légaré, Victor M. Montori, L. Trevena, G. Elwyn   +7 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Behavioural changes in exposure patterns after genetic counselling among asymptomatic first-degree relatives of patients with pulmonary fibrosis and carriers of a telomere-related gene variant. [PDF]

ERJ Open Res
Sesé L, Bouvry D, Kannengiesser C, Wémeau-Stervinou L, Jouneau S, Prevot G, Vagnarelli S, Guérin C, Lassus A, Crestani B, Bonniaud P, Cottin V, Gueguen S, Nunes H, Borie R.   +14 more
europepmc   +1 more source

Nothopegia castanaefolia: World Conservation Monitoring Centre

, 1998
IUCN
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source