Results 241 to 250 of about 4,506,201 (347)

Natural enviroment in the leisure-time centres education : A qualitative study with teachers in the leisure-time center

, 2018
Sjögren, Madelene, Rydbeck, Annica
openalex   +1 more source

Exploring the social function of congregations: A community development approach to develop ‘hub-and-spill’ early childhood development centres

, 2019
Marichen Van der Westhuizen, Rina Smith, Jacques Beukes   +2 more
openalex   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Exploring the psychological health of emergency dispatch centre operatives: a systematic review and narrative synthesis

, 2017
Sarah E. Golding, Claire Horsfield, Annette Davies, Bernadette Egan, Martyn C. Jones, Mary Raleigh, Patricia Schofield, Allison Squires, Kath Start, Tom Quinn, Mark Cropley   +10 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Natural ovulation versus programmed regimens before frozen embryo transfer in ovulatory women: multicentre, randomised clinical trial.

BMJ
Wei D, Qin Y, Sun Y, Yan J, Zhao H, Guan Y, Tan J, Guo T, Wang Z, Gong F, Hao C, Ma X, Zhang C, Zhang A, Geng L, Sun M, Li X, Ling X, Lu Q, Bao H, Chao L, Huang W, Shi Q, Zhao J, Lu Y, Wu S, Zhang S, Wang J, Guo M, Sun X, Ma Y, Wu Q, Li Y, Ou X, Fang Z, Chen J, Hao G, Zhang H, Legro RS, Chen ZJ, PnROVE Study Group.   +40 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Quantitative Imaging Advances in HPV-Positive Oropharyngeal Carcinoma. [PDF]

Cancers (Basel)
Farrell D, Bahig H, Khor R, Kowalski LP, de Bree R, Eisbruch A, Bollen H, Lopez F, Sreeram MP, Guntinas-Lichius O, Rodrigo JP, Saba NF, Rao KN, Nuyts S, Araújo ALD, Ferlito A, Ng SP.   +16 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Detection of an outbreak of Mediterranean spotted fever in Primary Care. [PDF]

Aten Primaria
Satorres Pérez M, García Molina C, Pérez Ortiz CI.   +2 more
europepmc   +1 more source