Results 91 to 100 of about 270,309 (306)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Effective sentence-level relation extraction model using entity-centric dependency tree [PDF]

open access: yesPeerJ Computer Science
The syntactic information of a dependency tree is an essential feature in relation extraction studies. Traditional dependency-based relation extraction methods can be categorized into hard pruning methods, which aim to remove unnecessary information, and
Seongsik Park, Harksoo Kim
doaj   +2 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Validity and reliability of intraoral conventional tracer and intraoral digital tracer in different positions for recording horizontal jaw relation in edentulous patients

open access: yesThe Journal of Indian Prosthodontic Society, 2019
Aim: The purpose of the study is to evaluate and compare the horizontal mandibular positions recorded between intraoral conventional tracer and intraoral digital tracer in upright and supine position.
Nikhil Bharat Abbad   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The Use of Mini-Plates for the Treatment of a High-Angle, Dual Bite, Class II Malocclusion

open access: yesTurkish Journal of Orthodontics, 2019
To present a case report of an orthodontic treatment of a high-angle, dual bite, Class II malocclusion without extractions and with the use of mini-plates.
Celha Borges Costa Alves   +2 more
doaj   +1 more source

Evaluating the perspective of patients with MS and related conditions on their DMT in relation to the COVID-19 pandemic in one MS centre in Australia [PDF]

open access: bronze, 2020
Nabil Seery   +15 more
openalex   +1 more source

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