Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Anterior temporalis and masseter muscle activity with different centric relation locating methods: A randomized cross-over trial. [PDF]
Sci RepNofal AT, Kois JC, Elbasty RS, Zaki AA.
europepmc +1 more source
Reproducibility of Centric Relation Techniques by means of Condyle Position Analysis. [PDF]
Acta Stomatol Croat, 2017 Galeković NH +3 more
europepmc +1 more source
Patient-Centred Care Dentistry And Its Relation With Maqasid Shari’ah: A Narrative Review
, 2023 Muhammad Annurdin Sabarudin +5 more
openalex +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Three-dimensional assessment of condylar position following orthognathic surgery using the centric relation bite and the ramal reference line: A retrospective clinical study. [PDF]
Medicine (Baltimore), 2019 Lee CH +5 more
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Accuracy of virtual mounting at centric relation using personalized 3D-printed transfer key: a clinical in vivo study. [PDF]
BMC Oral HealthHuynh NC +8 more
europepmc +1 more source
Arguing over the definitions and its implication: Reconsidering centric relation in dentistry [PDF]
, 2018 Zhongjie Li, Tingting Lan, Liu Yang
openalex +1 more source