Results 31 to 40 of about 4,918 (254)

A Review of Bionic Structures in Control of Aerodynamic Noise of Centrifugal Fans

open access: yesEnergies, 2023
Due to the complexity of the working conditions and the diversity of application scenarios, the normal operation of a fan, whether volute tongue, volute shell surface, or blade, often encounters some unavoidable problems, such as flow separation, wear ...
Wenqiang Zhou   +5 more
doaj   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Parc des ventilateurs et des résistances dans les techniques de séchage adaptées à l'environnement tropical [PDF]

open access: yesTropicultura, 1999
Fans and Resistances Park in Drying Technologies Appropriate for Tropical Environment. To design a dryer, it is necessary to master its elements. Fan and resistance are parts of heated and convective dryer.
Kapseu, C.   +4 more
doaj  

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

open access: yesAdvanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo   +5 more
wiley   +1 more source

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng   +17 more
wiley   +1 more source

Simulated Centrifugal Fan Blade Fault Diagnosis Based on Modulational Depthwise Convolution–One-Dimensional Convolution Neural Network (MDC-1DCNN) Model

open access: yesMachines
Existing intelligent fault diagnosis methods have been widely developed and proven to be effective in monitoring the operating status of key mechanical components.
Zhaohui Ren   +5 more
doaj   +1 more source

Design of Centrifugal Fan with Flexible Blades to Extend the Effective Operating Range in Various Speeds and Mass Flows Based on Numerical Analysis and Statistical Computation [PDF]

open access: yesJournal of Applied and Computational Mechanics
This paper presents research on raising the efficiency and pressure of centrifugal fans at different speed ranges. This problem is related to the incompatibility of the fan characteristics with the speed conditions of the impeller and flow conditions of ...
Thai Hiep, Le Long, Vu Thang, Hong Thong
doaj   +1 more source

Noise from Centrifugal Fans [PDF]

open access: yesThe Journal of the Acoustical Society of America, 1955
The sound power radiated from the discharge of centrifugal fans of diameters between 3 and 612 inches has been measured as a function of fan dimensions and operating conditions. The measurements were made by arranging the fan under test to discharge into an 11 foot nonreflecting tube in which the static pressure could be controlled.
R. B. Goldman, G. C. Maling
openaire   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang   +8 more
wiley   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

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