Results 101 to 110 of about 33,700 (260)
Advanced Science, EarlyView.A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang +14 more
wiley +1 more source
Advanced Science, EarlyView.Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng +19 more
wiley +1 more source
Advanced Science, EarlyView.In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu +7 more
wiley +1 more source
Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
Advanced Science, EarlyView.This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li +8 more
wiley +1 more source
Advanced Science, EarlyView.The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong +6 more
wiley +1 more source
Mechanical analysis on diamond saw blade based on ANSYS Workbench
Jin'gangshi yu moliao moju gongcheng, 2017 An analysis model for dry cutting saw blades was estbalished.The status of saw blade's stress was analyzed by means of finite element software ANSYS Workbench.The magnitude and distribution of the stress were concluded under the action of centrifugal ...
LI Yang, WANG Yanjun, QIN Ke
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Small diameter blood vessels with controllable micropore structure induced by centrifugal force for improved endothelialization. [PDF]
Eng Life Sci, 2020 Li J, Gao Q, Chen Z, Yang X.
europepmc +1 more source
Sonoselective Transfection of Glioma Endothelium
Advanced Science, EarlyView.Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski +8 more
wiley +1 more source
Jixie chuandong, 2012 Adaptive centrifugal of mechanical friction damp transmission system is designed,by using the character about centrifugal changing with velocity,adaptive velocity control function of mechanical transmission system is realized.The whole system includes ...
陈明
doaj
Crosslinked Pore-Filling Anion Exchange Membrane Using the Cylindrical Centrifugal Force for Anion Exchange Membrane Fuel Cell System. [PDF]
Polymers (Basel), 2020 Son TY, Kim TH, Nam SY.
europepmc +1 more source