Results 71 to 80 of about 33,700 (260)
Литьë и металлургия, 2007 The influence of centrifugal force on dynamics of the burning wave spread and the carbide particles distribution in metallic alloy in the process of SVS-casting is considered.
V. V. Hubovich +2 more
doaj
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Centrifugal Force and D' Alembert's Principle [PDF]
Nature, 1889 I agree so cordially with the greater part of Prof. Minchin's address to the Association for the Improvement of Geometrical Teaching, delivered on January 19, 1889, and reported in NATURE of June 6, p. 126, that I feel the more induced to enter a protest against his remarks on the subject of “centrifugal force.”
openaire +2 more sources
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Advanced Science, EarlyView.This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng +7 more
wiley +1 more source
On the impeller wear of vertical centrifugal pump carrying water–sand two-phase flow with fine particles: Characteristics and mechanisms [PDF]
AIP AdvancesLarge-scale vertical centrifugal pumps are widely used in the water diversion projects in China, and the pumping stations often operate in the river environments with suspended sediments. The problem of impeller wear caused by sediment-laden flow is very
Chunxun He +11 more
doaj +1 more source
A Centrifugal-Force-Driven Nano-Replication Strategy. [PDF]
Nanomaterials (Basel), 2023 Zhao W, Lin F, Han X.
europepmc +1 more source
Advanced Science, EarlyView.Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang +8 more
wiley +1 more source
Advanced Science, EarlyView.A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Advanced Science, EarlyView.Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source