Results 91 to 100 of about 395,081 (276)

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +2 more sources

Comparison Of Positive Displacement And Centrifugal Pump Applications

open access: yes, 1997
Tutorialpg. 99Positive displacement and centrifugal pumps sometimes seem to inhabit different worlds. Users are generally much more familiar with one type than the other.
Silvaggio, Joseph A., Purcell, John E.
core   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen   +13 more
wiley   +1 more source

Centrifugal Pumps Inspection And Testing

open access: yes, 1995
Tutorialpg. 143The general requirements for inspection and testing of centrifugal pumps are presented. The successful completion of inspection and testing verifies pump design and specification compliance prior to release of pump for shipment and helps ...
Patel, Vinod P., Bro, James R.
core   +1 more source

Intratumoral Fusogenic Outer Membrane Vesicles Enhance Antitumor Immunity Through Tumor MHC‐I Upregulation and Tumor Bacterization

open access: yesAdvanced Science, EarlyView.
Tumor bacterization by fusogenic outer membrane vesicles enhances microbial‐like recognition of tumor cells while activating the TLR4–NF‐κB–NLRC5 axis to upregulate MHC class I expression. By simultaneously strengthening APC sensing and T‐cell recognition, this strategy breaks tumor immune invisibility and promotes more effective antitumor immune ...
Xing Liu   +9 more
wiley   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

Forces On Centrifugal Pump Impellers

open access: yes, 1985
Lecturepg. 21Forces are exerted on a centrifugal pump impeller, due to the asymmetry of the flow caused by the volute or diffuser, and to the motion of the center of the impeller whenever the shaft whirls. Recent work in the measurement of these factors,
Acosta, Allan J.   +3 more
core   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Cavitation inception in fast startup [PDF]

open access: yes, 2008
The start-up of rocket engine turbopumps is generally performed only in a few seconds. It implies that these pumps reach their nominal operating conditions after only a few rotations.
Bois, Gérard   +5 more
core  

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