Results 81 to 90 of about 89,656 (296)

Аналіз ефективності роботи відцентрового насоса на основі його термодинамічної моделі [PDF]

open access: yes, 2007
Разработана математическая модель центробежного насоса на основании термодинамического подхода, определены термодинамические параметры для серии центробежных насосов магистральных нефтепроводов.
Костишин, В. С.   +1 more
core  

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Study on solid–liquid two-phase flow characteristics of centrifugal pump impeller with non-smooth surface

open access: yesAdvances in Mechanical Engineering, 2019
In order to improve the working performance of the solid–liquid two-phase flow in centrifugal pump, the current study attempted to probe into the influence of the solid-phase particle concentration on the characteristics of centrifugal pump and the drag ...
Yunqing Gu   +5 more
doaj   +1 more source

Rotating and positive-displacement pumps for low-thrust rocket engines. Volume 1: Pump Evaluation and design [PDF]

open access: yes
Rotating and positive displacement pumps of various types were studied for pumping liquid fluorine for low-thrust, high-performance rocket engines. Included in the analysis were: centrifugal, pitot, Barske, Tesla, drag, gear, vane, axial piston, radial ...
Csomor, A., Macgregor, C.
core   +1 more source

Assessment of Mechanical Problems for Centrifugal Pumps in Eastern Uttar Pradesh, India [PDF]

open access: yes, 2018
Centrifugal pumps are vital property of the agriculture sector. A good quality pump can assure uninterrupted water supply to irrigate crops. The consumer of agriculture sector is largely illiterate and shortcoming of the pumps is faced by farmers in the ...
Kumar, E. A. (Er)   +2 more
core  

The Effect of Inlet Swirl on the Rotordynamic Shroud Forces in a Centrifugal Pump [PDF]

open access: yes, 1992
The role played by fluid forces in determining the rotordynamic stability of a centrifugal pump is gaining increasing attention. The present research investigates the contributions to the rotordynamic forces from the discharge-to-suction leakage flows ...
Acosta, A. J.   +3 more
core   +2 more sources

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

Numerical Investigations on the Transient Performance of a Centrifugal Pump [PDF]

open access: yes
Centrifugal pumps are an integral part of plants used in process industries. The flow structure within a centrifugal pump is very complex due to the interaction between the rotating impeller and the geometric features around it.
Asim, Taimoor, Mishra, Rakesh
core  

Centrifugal-Pump Performance as Affected by Design Features [PDF]

open access: yes, 1941
This paper presents some of the results of a study of Grand Coulee pumping-plant characteristics. The research program was conducted for the Bureau of Reclamation by the California Institute of Technology in its hydraulic machinery laboratory (1) and
Knapp, R. T.
core  

Home - About - Disclaimer - Privacy