Results 111 to 120 of about 89,179 (297)

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

open access: yesBiotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal   +5 more
wiley   +1 more source

Design and test of a pump failure anticipator [PDF]

open access: yes
Tests were conducted on two different types of pumps in order to refine the concept and to finalize design details of a positive displacement internal gear pump and a shroudless centrifugal pump.
Burchill, R. F.   +2 more
core   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

open access: yesBiotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Introduction of a Data‐Based Preliminary Compressor Design for Mechanical Vapor Compression

open access: yesChemie Ingenieur Technik, EarlyView.
This work proposes a data‐driven methodology for the design of compressors for mechanical vapor compression, with the objective of electrification of chemical processes utilizing renewable energy sources. This approach enables the determination of suitable compressor architectures and their performance parameters within the framework of a potential ...
Lars Hinz   +4 more
wiley   +1 more source

Simulation of Three Dimensional Flows in Hydraulic Pumps [PDF]

open access: yes, 2011
Hydraulic efficiency of the centrifugal pump is mainly depends on mass flow rate, Head and RPM. Finding the best combination with the above said parameters and the best geometry of the pump is possible by using three dimensional CFD simulations.
PremaKumara, G.   +2 more
core  

A Short‐Cut Design Approach to Evaluate Reboiler Designs in Vapor Recompression Scenarios

open access: yesChemie Ingenieur Technik, EarlyView.
A short‐cut model framework that incorporates mechanical vapor recompression (MVR) requirements into reboiler design is presented, which is particularly beneficial during early process development with limited data or initial feasibility assessments.
Franziska Lais   +2 more
wiley   +1 more source

Assessment of Mechanical Problems for Centrifugal Pumps in Eastern Uttar Pradesh, India [PDF]

open access: yes, 2018
Centrifugal pumps are vital property of the agriculture sector. A good quality pump can assure uninterrupted water supply to irrigate crops. The consumer of agriculture sector is largely illiterate and shortcoming of the pumps is faced by farmers in the ...
Kumar, E. A. (Er)   +2 more
core  

3D‐Printed Coil Immobilized Enzyme Reactors for Laccase Biocatalysis in Single‐ and Two‐Phase Flow

open access: yesChemie Ingenieur Technik, EarlyView.
Development of 3D‐printed immobilized enzyme reactors functionalized with laccase for continuous‐flow biocatalysis. Surface coupling and reactor design enhanced stability and mass transfer, enabling efficient and reusable biocatalytic processes.
Alina J. Tauriainen   +4 more
wiley   +1 more source

Rotating-Pump Design Code [PDF]

open access: yes
Pump Design (PUMPDES) is a computer program for designing a rotating pump for liquid hydrogen, liquid oxygen, liquid nitrogen, water, methane, or ethane.
Chen, Shu-Cheng   +2 more
core   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

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