Results 121 to 130 of about 208,778 (199)

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Consistency in bacterial extracellular vesicle production: key to their application in human health. [PDF]

Extracell Vesicles Circ Nucl Acids
Dai K, Liao B, Huang X, Liu Q.
europepmc   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Establishment and Characteristics of the Spermatogonial Stem Cell Line from the Yellow River Carp (<i>Cyprinus carpio haematopterus</i>). [PDF]

Biology (Basel)
Zhou H, Liu T, Zhang T, Sun Z, Xu H, Zhang T, Yin Y, Li N, Yan T, Kuang Y.   +9 more
europepmc   +1 more source

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

Advanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara, Emma R. Brannon, Daniel Kupor, Mariana R.N. Lima, Logan D. Piegols, Michael L. Felder, Kathryn E. Uhrich, Omolola Eniola‐Adefeso   +7 more
wiley   +1 more source

Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair. [PDF]

J Cell Biol
Williams JK, Ngo JM, Murugupandiyan A, Croall DE, Hartzell HC, Schekman R.   +5 more
europepmc   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Surface-Enhanced Raman Spectroscopy on Gold Nanoparticle for Sperm Quality Discrimination. [PDF]

Molecules
Lopez-Lora YP, Galán-Freyle NJ, Vidal-Figueroa N, Cardozo-Puello AA, Acosta-Hoyos AJ, Parra-Anaya G, Lebrón-Ramírez ES, Espitia-Almeida F, Hernández-Rivera SP, Méndez-López M, Fiorillo-Moreno O, Rondon-Payare K, Pacheco-Londoño LC.   +12 more
europepmc   +1 more source

Generalizing Gelatin Methacryloyl Granular Hydrogel Fabrication Using Stable Microgels with Predictable Stiffness

Advanced Healthcare Materials, EarlyView.
Gelatin methacryloyl (GelMA) granular hydrogel scaffolds (GHS) are fabricated using a generalized two‐step photocrosslinking approach to yield stable (non‐dissolving) microgels suitable for in situ covalent assembly under physiological conditions. A phase diagram is developed to define the interplay between individual microgel stability and scaffold ...
Yuanhui Xiang, Zaman Ataie, Angie Castro, KyungBae Woo, Amir Sheikhi   +4 more
wiley   +1 more source