Results 131 to 140 of about 380,843 (313)

A P-glikoprotein membrán mikrokörnyezete és működésének gátolhatósága modulátor és antitest együttes alkalmazásával = P-glycoprotein membrane microenviroment and inhibition of pumping by the combined application of modulators and specific antibody [PDF]

, 2009
A multidrog rezisztencia hátterében gyakran a P-glikoprotein (Pgp) pumpa működése áll, melynek gátlására jelentős erőfeszítések történnek világszerte. Az UIC2 antitest a fehérjét katalitikus ciklusa egy fázisában ismeri fel, és ott blokkolja.
Bacsó, Zsolt, Fenyvesi, Ferenc, Goda, Katalin, Szabó, Gábor   +3 more
core  

Electrically Tunable On‐Chip Topological Photonics with Integrated Carbon Nanotubes

Advanced Functional Materials, EarlyView.
This work demonstrates electrically tunable on‐chip topological THz devices by integrating 2D carbon nanotube (CNT) sheets with valley‐Hall photonic crystals, enabling broadband transmission modulation (71% modulation depth) and tunable narrowband filtering (0.54 GHz shift) through electrically induced thermal tuning. This advancement paves the way for
Jifan Yin, Wenhao Wang, Thomas Caiwei Tan, Abhishek Kumar, Ridong Jia, Nikhil Navaratna, Ranjan Singh, Lijuan Xie   +7 more
wiley   +1 more source

Comparative Efficacy of Swim-Up, Density-Gradient Centrifugation, and Microfluidic Sorting in Sperm Preparation, and the Impact on Motility, Morphology, and DNA Integrity

International Journal of General Medicine
Zi-Na Wen, Li Duan, Yong Chen, Qing-Hong Qiu, Gang Liu, Ning Luo, Peng-Hao Li, Er-Po Tian, Ren-Shan Ge Andrology Laboratory, Sichuan Jinxin Xinan Women and Children Hospital, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Ren-Shan Ge ...
Wen ZN, Duan L, Chen Y, Qiu QH, Liu G, Luo N, Li PH, Tian EP, Ge RS   +8 more
doaj  

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Complementary Logic Driven by Dielectrophoretic Assembly of 2D Semiconductors

Advanced Functional Materials, EarlyView.
Scalable, parallel fabrication of complementary logic gates is demonstrated using electric‐field‐driven deterministic assembly of electrochemically exfoliated 2D n‐type MoS2 and p‐type WSe2 nanosheets. This strategy yields MoS2 and WSe2 transistors featuring average mobilities of 4.3 and 3.0 cm2 V−1 s−1, respectively, and on/off ratios of > 104 ...
Dongjoon Rhee, Okin Song, Ji Yun Park, Yonghyun Albert Kwon, Jae Hyung Kim, In Soo Kim, Zdeněk Sofer, Jeong Ho Cho, Deep Jariwala, Hyesung Park, Joohoon Kang   +10 more
wiley   +1 more source

Density Gradient Centrifugation [PDF]

, 2020
openaire   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

Advanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee, Dongjo Yoon, Jungha Lee, Duhee Kim, Eunui Kim, Jong‐Hyeok Yoon, Hyuk‐Jun Kwon, Seungjun Chung, Yoonkey Nam, Hongki Kang   +9 more
wiley   +1 more source