Results 131 to 140 of about 208,778 (199)

Optimized enrichment of murine blood-brain barrier vessels with a critical focus on network hierarchy in post-collection analysis. [PDF]

open access: yesSci Rep
Abdelazim H   +9 more
europepmc   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang   +10 more
wiley   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng   +5 more
wiley   +1 more source

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy