Results 131 to 140 of about 495,738 (354)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
New Proposal for a Gas Centrifuge Rotating Differentially [PDF]
Takuya Matsuda
openalex +1 more source
Centrifuge impact cratering experiments: Scaling laws for non-porous targets [PDF]
A geotechnical centrifuge was used to investigate large body impacts onto planetary surfaces. At elevated gravity, it is possible to match various dimensionless similarity parameters which were shown to govern large scale impacts.
Schmidt, Robert M.
core +1 more source
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Liquid-retention characteristics of diesel-contaminated soil considering water-diesel separation
To investigate the liquid-retention characteristics of soils with immiscible liquid of water and diesel, and analysis the distribution and evolution of pore water-diesel during the dehumidification process, a centrifuge method is used to test the liquid ...
HUA Longfei 1, 2, WAN Yong 1, CHEN Zhixiang 1 , LI Shunqun 2
doaj +1 more source
Influence of changing feed flow value on germanium isotope separation in gas centrifuge cascade
А. А. Ushakov +2 more
openalex +1 more source

