Results 241 to 250 of about 495,738 (354)

Humanized Mouse Models of Epstein Barr Virus Infection. [PDF]

Curr Protoc
von Boxberg SG, Gehrmann K, Nopper SL, Romann L, Kösegi S, Münz C.   +5 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Protocol for optimized mononuclear cell isolation from liver and tumor tissue using mechanical or enzymatic digestion. [PDF]

STAR Protoc
Chauhan SKS, Feldbrügge L, Schmelzle M, Wedemeyer H, Heinrich B.   +4 more
europepmc   +1 more source

ANALYSIS OF GEOMETRICAL SPECIFICATION IN DECANTER CENTRIFUGE MACHINE

, 2018
Bagus Budiwantoro, Indra Djodikusumo, Ade Ramdan   +2 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Artemis: Mass Spectrometry-Based Identification of MHC-Presented Peptides Across Alleles, Classes, and Species Using Soluble Single-Chain MHC Constructs. [PDF]

Methods Mol Biol
Finton KAK, Foote-McNabb UN, Wilcox EC, Jones LA, Gafken PR, Strong RK.   +5 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Protocol for stable isotopic tracing to assess cellular lipogenic activity in induced neural stem cells. [PDF]

STAR Protoc
Ionescu RB, Reisz JA, Dzieciatkowska M, Stephenson D, Nicaise AM, Prasad P, Willis CM, Cubero MS, Peruzzotti-Jametti L, Edenhofer F, Frezza C, Pluchino S, D'Alessandro A.   +12 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

FLARE: A Flow Cytometry-Based Fluorescent Assay for Measuring HSV-1 Nuclear Egress. [PDF]

Bio Protoc
Dai B, Polack L, Moores S, Calderon-Zavala AC, Heldwein EE.   +4 more
europepmc   +1 more source