Results 71 to 80 of about 23,096 (306)
Centrifuge modeling to support the design of subsea pipelines
, 2012 Offshore geotechnical engineering is characterized by unusual soil and loading conditions, a continuously moving frontier resulting in the requirement for innovative geotechnical solutions, and the very high cost associated with in-situ soil ...
D. J. White +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Modelling failure mechanisms of soft cliff profiles
, 2006 A large proportion of the 11,000 km coastline of the United Kingdom is backed by soft cliffs. These cliffs are subject to frequent slumping and landslip events, particularly where sea and ground water percolates into the soil and rock.
Sentenac, P. +4 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Simulation of dynamic loading in centrifuge modeling for suction bucket foundations [PDF]
, 2005 Suction bucket foundations are widely used in the offshore platform for the exploitation of the offshore petroleum and natural gas resources in the Bohai Bay of China.
Lu, XB (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China. +4 more
core
Response of Monopiles Under Lateral Loading By Centrifuge Modeling
نشریه مهندسی دریا, 2016 One of the most common methods to analyze and design monopiles under lateral load is load-displacement curves, particularly the p-y curves, at different locations of the structure.
Hamid Reza Khodaei +2 more
doaj
Journal of Petroleum Exploration and Production Technology, 2018 The production from oil and gas reservoirs is greatly affected by rock and fluid properties of the porous rock. Capillary pressure (P c) and relative permeability (k r) are two important properties employed in the mathematical simulation reservoirs for ...
Muhammad Yaralidarani +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Centrifuge modeling of monopiles
, 2010 To gain a larger knowledge of the monopile foundation concept, centrifuge modeling is used by the geotechnical group at DTU. The centrifuge operated at DTU is a beam centrifuge and was built in 1976.
Klinkvort, Rasmus Tofte
core
Feasibility Study of Centrifuge Modeling of SAGD Caprock Integrity
, 2016 The Joslyn steam release incident in 2006 has significantly influenced the approval process for steam assisted gravity drainage (SAGD) projects, which now require rigorous caprock integrity assessment to be conducted.
Wu, Jingyu
core +1 more source