Results 81 to 90 of about 2,483,895 (292)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Centrifuge modeling of a large-scale surcharge on adjacent foundation

Journal of Rock Mechanics and Geotechnical Engineering
This study investigates the ground and structural response of adjacent raft foundations induced by large-scale surcharge by ore in soft soil areas through a 130g centrifuge modeling test with an innovative layered loading device.
Jinzhang Zhang, Zhenwei Ye, Dongming Zhang, Hongwei Huang, Shijie Han, Tong Zou, Le Zhang   +6 more
doaj   +1 more source

Co-estimation of saturation functions (k r and P c) from unsteady-state core-flood experiment in tight carbonate rocks

Journal of Petroleum Exploration and Production Technology, 2018
The production from oil and gas reservoirs is greatly affected by rock and fluid properties of the porous rock. Capillary pressure (P c) and relative permeability (k r) are two important properties employed in the mathematical simulation reservoirs for ...
Muhammad Yaralidarani, Hamidreza Shahverdi   +1 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Pile-Reinforcement Behavior of Cohesive Soil Slopes: Numerical Modeling and Centrifuge Testing

Journal of Applied Mathematics, 2013
Centrifuge model tests were conducted on pile-reinforced and unreinforced cohesive soil slopes to investigate the fundamental behavior and reinforcement mechanism. A finite element analysis model was established and confirmed to be effective in capturing
Liping Wang, Ga Zhang
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Simulation of dynamic loading in centrifuge modeling for suction bucket foundations [PDF]

, 2005
Suction bucket foundations are widely used in the offshore platform for the exploitation of the offshore petroleum and natural gas resources in the Bohai Bay of China.
Zhang JH, Chen ZY, Sun GL, Lu XB(鲁晓兵)   +3 more
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source