Results 151 to 160 of about 1,590,241 (290)
DEM simulation of earth pressure mobilisation with active retaining wall movements. [PDF]
Sci RepHe D, Guo J, Cui L.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A Review of Modelling Test Study on the Effect of Single-Line Tunnelling on Adjacent Piles: Test Materials, Methodologies and Results. [PDF]
Materials (Basel)Diao H, Lu Y, Hu H, Wei G, Li Q, Zhou X.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Centrifuge model study on consolidation characteristics of sand-based fill soil subjected to pulse-induced water bag + vacuum preloading. [PDF]
Sci RepChen Q, Xu X, Wang G, Zhou W, Feng Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Diagnostic accuracy of rapid and point-of-care tests for <i>Schistosoma haematobium</i> in African populations: a systematic review and meta-analysis. [PDF]
Front ParasitolDraxl E, Ochodo E, Pillay P, Ndlovu N.
europepmc +1 more source
Centrifuge Model Tests on tunnel excavation
Proceedings of the Japan National Conference on Geotechnical Engineering, 2003 TAKAHASHI, Shinichi +4 more
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source