Results 41 to 50 of about 15,964,666 (310)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Test technology for modeling underwater explosion in centrifuge
Yantu gongcheng xuebaoWith the increasing tension in the international arena, the anti-explosion safety of important infrastructures has attracted increasing attention. For the study on underwater explosion, the centrifugal model tests are an important method to study the ...
HU Jing , CHEN Zuyu , LEI Yumeng , WANG Yunchao , ZHANG Zitao , ZHANG Xuedong
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Numerical Study of Internal Flow Field in a Disc Stack Centrifuge Based on Mixture-PBM Model
Applied SciencesDisc stack centrifuge belongs to one kind of sedimentation centrifuge, widely used in the environmental protection, pharmacy, and chemical industries, etc.
Hefeng Dong +7 more
doaj +1 more source
Centrifuge model test study on micro-pile reinforcement of shallow foundation
Soils and Foundations, 2023 Micro-piles are an effective reinforcement measure for existing foundations in practice. A series of centrifuge model tests were conducted on different combinations of shallow foundation and micro-piles to investigate the reinforcement effect of micro ...
Zixi Li, Ga Zhang
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Settlement Prediction of Footings Using VS
Applied Sciences, 2017 The shear wave velocity (VS) is a key parameter for estimating the deformation characteristics of soil. In order to predict the settlement of shallow footings in granular soil, the VS and the concept of Schmertmann’s framework were adopted.
Hyung Ik CHO +3 more
doaj +1 more source
Recent centrifuge modelling of offshore geotechnical problems at IWHR [PDF]
E3S Web of Conferences, 2019 Centrifuge modelling has been proven to be an efficient and reliable approach for examining offshore geotechnical problems. This study reports the two series of centrifuge tests to understand the behaviour of spudcan penetration in a “soft-stiff-soft ...
Liang Jianhui, Song Xianhui
doaj +1 more source