Results 81 to 90 of about 15,964,666 (310)

Numerical Validation of Fully Coupled Nonlinear Seismic Soil–Pile–Structure Interaction

Buildings
While many researchers have broadly studied soil–structure interaction (SSI) problems to comprehend SSI effects on the overall system’s behavior, some critical numerical modeling issues have not been sufficiently investigated to achieve the most accurate
Oğuzhan Çetindemir, Abdullah Can Zülfikar   +1 more
doaj   +1 more source

The Deformation Characteristics of Weak Foundation with High Back Siltation in the Immersed Tunnel

Advances in Materials Science and Engineering, 2018
The deformation characteristics of a weak foundation with high back siltation in an immersed tunnel lack empirical data; however, the calculation method and control of foundation settlements are highly important to tunnel design and construction.
Xiabing Yue, Yuan Xie, Yongli Xie
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Centrifuge tests on stability of tunnel face in sand-clay layered strata with different interlayer angles

Yantu gongcheng xuebao
Based on centrifuge model tests, this study systematically investigates the stability of a shield tunnel face in sand-clay composite strata for different interlayer inclination angles and interface positions.
LI Xuancong 1, 2, WENG Xiaolin 1, 2, YE Fei 1, 2, DENG Guohua 3, DANG Bohan 1, 2, ZHANG Xinye 1, 2
doaj   +1 more source

Calibration of the Performance of Bidirectional Shaker Table in Centrifuge Model Tests Using Sensor Networks

International Journal of Distributed Sensor Networks, 2013
Great concern for the safety of high rock-fill dams which are being or to be built in the southwestern area of China with high seismicity is attracted.
Hongjun Li, Hong Zhong, Xuedong Zhang, Yanyi Zhang, Yujing Hou   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Small-displacement behavior of offshore wind power monopiles subjected to static lateral loading

Yantu gongcheng xuebao
The centrifuge tests and numerical simulations are carried out to explore the small-displacement behavior of 9 m-diameter offshore wind power large-scale monopiles with various embedment depths. The results show that as the embedment depth increases, the
WANG Wei 1 , ZHANG Zitao 2 , YU Guangming 1, ZHANG Xuedong 2, ZHANG Zechao 1, SONG Jianzheng 2, ZHANG Zheng 2
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source