Results 71 to 80 of about 15,964,666 (310)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Centrifuge Tests of Dyke Collapses on Soft Subsoil
This paper presents the results of an experimental investigation on the failure or collapse of dykes with a strong contrast of stiffness between the dyke itself and its foundation layers. In deltaic regions, dykes are commonly built out of stiff sandy or clayey materials and rest on soft foundations layers (e.g. soft clay or peat). Their interaction is
Fern James +3 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
LEAP-UCD-2017 Centrifuge Tests at Cambridge [PDF]
As part of the LEAP project the seismic response of a liquefiable 5° slope was modelled at a number of centrifuges around the world. In this paper the two experiments conducted at Cambridge University are discussed. The model preparation is detailed with particular emphasis on the sand pouring, saturation and slope cutting process.
Srikanth S. C. Madabhushi +4 more
openaire +2 more sources
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
I dette prosjektet har en sentrifugalpumpe for elektriske motorer blitt undersøkt. En rask progresjon innen batteriteknologi og elektrisk utstyr de siste årene, har gjort det mulig å erstatte de mer tradisjonelle gassturbin-pumpene med elektriske pumper. Slike pumper er typisk mer fleksible, billigere og tryggere, samt enklere for parametrisk skalering.
openaire +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Centrifuge Model Tests of Nailed Soil Slopes
This paper presents the results of 24 centrifuge model tests of nailed soil slopes and vertical walls, constructed out of dry Leighton buzzard sand. The walls were initially supported by fluid pressure from flexible rubber bags against the face, and excavation was modelled by gradually draining the fluid from the bags. The finished model walls were 200
TEI, KOUJI +2 more
openaire +2 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

