Results 31 to 40 of about 273,730 (211)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
The UCD’s disintegration: state of investigations
El Futuro del Pasado, 2011 The history of the UCD is intense. It is a party built from the power to carry out the transition. A party that meets perfectly his role and that connecting with voters. However, disappears just six years after his appearance.
J. Daniel Molina Jiménez
doaj
La periferia latinoamericana en el sistema global del capitalismo
El Trimestre Económico, 2022 Este artículo constituye una apretada síntesis de las principales ideas del autor, las que se despliegan en tres ámbitos íntimamente vinculados entre sí.
Raúl Prebisch
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Las relaciones centro-periferia en la Unión Europea después de la covid
El Trimestre Económico, 2022 La pandemia ha provocado en la Unión Europea la mayor caída del producto interno bruto (PIB) per cápita de su historia. La respuesta de las autoridades comunitarias ha sido excepcional y se ha puesto en marcha un fondo de recuperación de 700 000 millones
Alberto Garzón Espinosa
doaj +1 more source
CENTRO, CENTRALIDADE E O PAR CENTRO-PERIFERIA
Estudos Geográficos: Revista Eletrônica de Geografia, 2021 Uma das tendências da urbanização contemporânea é a subversão da estrutura urbana pautada no par centro-periferia, por meio da passagem de uma estrutura monocêntrica para uma estrutura multicêntrica ou, até mesmo, policêntrica. Este trabalho investiga a estrutura urbana de Presidente Prudente/SP sob égide do par centro-periferia, encetando debates e ...
null LAÉRCIO YUDI WATANABE SILVA +1 more
openaire +2 more sources
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
La estética de la irreverencia: maltraducir desde los márgenes
Mutatis Mutandis, 2011 Nos proponemos indagar la potencia que los postulados irreverentes borgianos aportan a la periferia geopolítica y literaria. Veremos que la esencia del potencial de la periferia radica en la conflictiva dualidad de lo local y lo extranjero (en el caso de
Sergio Waisman, Marcelo Cohen
doaj +3 more sources
RevistArquis, 2016 El Proyecto TETR@S se encuentra ubicado en el Paso de la Vaca, San José, Costa Rica. Forma parte del plan maestro de regeneración de dicha zona y su objetivo principal es el generar apertura y reactivar los centros de cuadra.
Vivian Caravaca
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source