Results 161 to 170 of about 3,631 (266)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Tuberculosis in the South America's homeless: a systematic review of social determinants, control strategies and health equity. [PDF]

Rev Esc Enferm USP
Ramos EM, Sisti CB, Lima SBA, Araújo ELL, Guerra LDDS, Polubriaginof C, Guimarães AMS.   +6 more
europepmc   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

[From words to deeds: Description and challenges in the implementation of social prescription in spanish primary care]. [PDF]

Aten Primaria
Carrera Noguero AM, Gilabert Mora M, Astier Peña MP, Mira JJ, Pérez-Jover V, Melús Palazón E.   +5 more
europepmc   +1 more source

Cumulative effect of multiple health and social factors on adolescent mental well‐being: a cross‐sectional study in Catalonia

Child and Adolescent Mental Health, EarlyView.
Background While numerous studies have explored factors contributing to poor mental health, few have examined the combined influence of multiple health and social factors and their cumulative effect. This study specifically aimed to analyze the cumulative effect of multiple health and social factors associated with poor mental well‐being in school‐aged
Marina Robles‐Muñoz, Marina Bosque‐Prous, Cinta Folch, Helena González‐Casals, Gemma Drou‐Roget, Cristina Torrado‐Cortés, Carles Muntaner, Albert Espelt   +7 more
wiley   +1 more source

[Reputational risks associated with nurses' presence on social media: proposed actions following the Vall d'Hebron case]. [PDF]

An Sist Sanit Navar
González-Luis H, Azurmendi A, Basanta-Vázquez B, Pujol F.   +3 more
europepmc   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

Clinical &Experimental Allergy, EarlyView.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos, Chen‐Yuan Chiang, M. Innes Asher, Guy B. Marks, Asma El Sony, Refiloe Masekela, Karen Bissell, Eamon Ellwood, Philippa Ellwood, Neil Pearce, David P. Strachan, A. Elena Martínez‐Torres, Manuel Sánchez‐Solís, Kevin Mortimer, Eva Morales, The Global Asthma Network Phase I Study Group   +15 more
wiley   +1 more source

[Social determinants, the urban environment, and public safety policies: a spatial ecological and time-series analysis of Santiago de Cali, Colombia, 2015-2024Determinantes sociais, ambiente urbano e políticas de segurança: análise ecológica espacial e de séries temporais em Santiago de Cali, Colômbia, 2015-2024]. [PDF]

Rev Panam Salud Publica
Pinzón-Flórez CE, Díaz Rivadeneira M, Escobar Morales G.   +2 more
europepmc   +1 more source

Bioarquitectura : jardín social y centro AMAR.

, 2003
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openaire   +1 more source

Promotion of Emotional Competencies in Auxiliary Grandparents Caregivers: A Pilot Prevention Programme

Child &Family Social Work, EarlyView.
ABSTRACT This study examined the efficacy of a 5‐week combined psychoeducation and support programme aimed at enhancing emotional competencies and psychological well‐being among Spanish auxiliary grandparent caregivers. Two delivery formats (face‐to‐face and synchronous online) were compared with a control group receiving no intervention, and ...
Cristina Noriega, Leyre Galarraga, Montserrat Celdrán, Javier López, Gema Pérez‐Rojo   +4 more
wiley   +1 more source