Results 121 to 130 of about 816 (137)

Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann

Toxicon, 1980
Abstract The venom from the scorpion Centruroides limpidus tecomanus Hoffmann was obtained by homogenization of entire telsons and electrical stimulation of anaesthetized animals. Both venom preparations contain toxic proteins to mice and were separated in a Sephadex G-50 column followed by carboxymethyl-cellulose chromatography. At least two toxic
Lourival Possani, Paul Fletcher
exaly   +3 more sources

Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus

Peptides, 2017
A previously undescribed toxic peptide named Cl13 was purified from the venom of the Mexican scorpion Centruroides limpidus. It contains 66 amino acid residues, including four disulfide bonds. The physiological effects assayed in 7 different subtypes of voltage gated Na+-channels, showed that it belongs to the β-scorpion toxin type.
Timoteo, Olamendi-Portugal, Rita, Restano-Cassulini, Lidia, Riaño-Umbarila, Baltazar, Becerril, Lourival D, Possani   +4 more
openaire   +2 more sources

Three-dimensional structure determination and comparison of two crustacean and one mammalian toxins from the venom of the scorpions Centruroides limpidus limpidus and noxius

Toxicon, 1996
F. Lebreton, C. Garcia, B. Becerril, L. Possani, M. Delepierre   +4 more
exaly   +2 more sources

Venom content and toxicity regeneration after venom gland depletion by electrostimulation in the scorpion Centruroides limpidus

Toxicon, 2019
The scorpion venom is a cocktail of many components. Its composition can exhibit a level of plasticity in response to different behavioral and environmental factors, leading to intraspecific variation. The toxicity and specificity of scorpion venoms appear to be taxon-dependent, due to a co-evolutionary interaction with prey and predators, which shaped
Edson Norberto Carcamo-Noriega, Lourival Domingos Possani, Ernesto Ortiz   +2 more
openaire   +2 more sources

Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann

Toxicon, 1988
The complete amino acid sequence of the major toxic component (II.20.3.4), named toxin 1, from the venom of the Mexican scorpion C. l. tecomanus is reported. The sequence (66 amino acids) was obtained by direct Edman degradation of reduced and alkylated toxin, followed by sequence determination of selected peptides separated after enzymatic cleavage ...
Martin BM, CARBONE, Emilio, Yatani A, Brown AM, Ramírez AN, Gurrola GB, Possani LD   +6 more
openaire   +3 more sources

<strong>Designing, cloning and amplification of pDream2.1/MCS/CII-6 recombinant plasmid which </strong><strong>includes a mexican scorpion <em>Centruroides limpidus limpidus </em>CII-6 gene</strong>

Proceedings of MOL2NET 2016, International Conference on Multidisciplinary Sciences, 2nd edition, 2016
Juan Carlos Vázquez-Chagoyán, José María Eloy Contreras-Ortiz, Alberto Barbabosa-Pliego   +2 more
exaly   +2 more sources

Comparative proteomic analysis of female and male venoms from the Mexican scorpion Centruroides limpidus: Novel components found

Toxicon, 2017
Venom from male and female scorpions of the species Centruroides limpidus were separated by HPLC and their molecular masses determined by mass spectrometry. The relative concentration of components eluting in equivalent retention times from the HPLC column shows some differences.
Jimena Isaias Cid Uribe, Juana Maria Jiménez Vargas, Cesar Vicente Ferreira Batista, Fernando Zamudio Zuñiga, Lourival Domingos Possani   +4 more
openaire   +2 more sources

Venom components of the scorpion Centruroides limpidus modulate cytokine expression by T helper lymphocytes: Identification of ion channel-related toxins by mass spectrometry

International Immunopharmacology, 2020
The study of the effector mechanisms of T helper cells has revealed different phenotypic characteristics that can be manipulated for designing new therapeutic schemes in different pathological scenarios. Ion channels are significant targets in T lymphocyte modulation since they are closely related to their effector activity.
Julián M, Cota-Arce, Daniela, Zazueta-Favela, Fernando, Díaz-Castillo, Samanta, Jiménez, Johanna, Bernáldez-Sarabia, Nadia L, Caram-Salas, Kee W L, Dan, Galileo, Escobedo, Alexei F, Licea-Navarro, Lourival D, Possani, Marco A, De León-Nava   +10 more
openaire   +2 more sources

Experimental envenoming of mice with venom from the scorpion Centruroides limpidus limpidus: differences in mortality and symptoms with and without antibody therapy relating to differences in age, sex and strain of mouse

Toxicon, 2003
C57Bl/6J and BALB/cAnN inbred strains of mice differed significantly in mortality and symptoms when intoxicated subcutaneously with one LD(50) of venom from Centruroides limpidus limpidus. Higher mortality was observed in C57Bl/6J than in BALB/cAnN. Also, C57Bl/6J mice more quickly developed muscular and respiratory collapse whilst BALB/cAnN mice were ...
Alejandro, Padilla, Tzipe, Govezensky, Lourival D, Possani, Carlos, Larralde   +3 more
openaire   +2 more sources

Immunity against the venom of Mexican scorpion Centruroides lumpidus limpidus induced by some proteins from this venom.

Annales d'immunologie, 1980
A protein fraction, which consisted of at least 12 proteins, was obtained from the venom of Mexican scorpion Centruroides limpidus limpidus. The molecular weights of these proteins ranged between 9,800 and 163,000 daltons. This fraction was separated from the rest of the venom components, which were almost all neurotoxins, by chromatographying the ...
J L, Molinari, P, Tato Zaldivar, L, Méndez   +2 more
openaire   +1 more source