Results 11 to 20 of about 177,089 (78)
Вопросы лесной наукиThis article presents the results and summary of the most important and interesting reports from the IX All-Russian (with international participation) scientific conference “Aerospace Methods and Geoinformation Technologies in Forest Science, Forestry ...
S. V. Knyazeva +13 more
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The current state of the art and future trends in RAS-targeted cancer therapies
Nature Reviews Clinical Oncology, 2022 Despite being the most frequently altered oncogenic protein in solid tumours, KRAS has historically been considered ‘undruggable’ owing to a lack of pharmacologically targetable pockets within the mutant isoforms.
S. Punekar +3 more
semanticscholar +1 more source
III All-Russian scientific conference (with international participation) “Scientific bases of sustainable forest management” [PDF]
Вопросы лесной науки, 2019 The article has been presents the review of the work of the III All-Russian Scientific Conference (with international participation) “Scientific basis for sustainable forest management”.
A.V. Gornov, A.P. Geraskina
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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy
Nature Cancer, 2021 Our understanding of how the RAS protein family, and in particular mutant KRAS, promotes metabolic dysregulation in cancer cells has advanced substantially over the last decade. In this Review, we discuss the metabolic reprogramming mediated by oncogenic
S. Mukhopadhyay +2 more
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Modern Library Potential as Science Popularizer: Inquiry Results of SB RAS Scientists
Proceedings of SPSTL SB RAS, 2023 The objective of the article is to present the results of a study of scientists’ attitude to communication between science and society by means of libraries.
Z. Vakhrameeva, I. Yudina
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State Public Scientific Technological Library of the SB RAS: a century-long journey
Proceedings of SPSTL SB RAS, 2023 One of the largest libraries in Russia on the Eurasian continent, the State Public Scientific Technological Library of the Siberian Branch of the Russian Academy of Sciences (SPSL SB RAS) in 2023 celebrates its 105th anniversary from the date of ...
A. L. Posadskov, I. Lizunova
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Ecography, Volume 43, Issue 7, Page 967-978, July 2020., 2020 Disturbance regimes are changing in forests across the world in response to global climate change. Despite the profound impacts of disturbances on ecosystem services and biodiversity, assessments of disturbances at the global scale remain scarce. Here, we analyzed natural disturbances in boreal and temperate forest ecosystems for the period 2001–2014 ...
Rupert Seidl +24 more
wiley +1 more source
The frequency of Ras mutations in cancer
Cancer Research, 2020 Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation frequency of Ras, with quoted values varying from 10%–30%. This variability is at least in part due to the selective aggregation of
I. Prior, Fiona E. Hood, J. Hartley
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Emerging strategies to target RAS signaling in human cancer therapy
Journal of Hematology & Oncology, 2021 RAS mutations ( HRAS , NRAS , and KRAS ) are among the most common oncogenes, and around 19% of patients with cancer harbor RAS mutations. Cells harboring RAS mutations tend to undergo malignant transformation and exhibit malignant phenotypes.
Kun Chen +3 more
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TGF-β Orchestrates Fibrogenic and Developmental EMTs via RAS Effector RREB1
Nature, 2020 Epithelial-to-mesenchymal transitions (EMTs) are phenotypic plasticity processes that confer migratory and invasive properties to epithelial cells during development, wound-healing, fibrosis and cancer1–4.
Jie Su +12 more
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