Results 271 to 280 of about 115,421 (318)
Some of the next articles are maybe not open access.
Obstetrics and Gynecology Clinics of North America, 1989
The cephalosporins have had a great effect on the prevention and treatment of many obstetric and gynecologic infections. Broader spectra and greater activity often allow for effective single-agent usage. Improved pharmacokinetics have permitted the number of doses to be decreased.
openaire +2 more sources
The cephalosporins have had a great effect on the prevention and treatment of many obstetric and gynecologic infections. Broader spectra and greater activity often allow for effective single-agent usage. Improved pharmacokinetics have permitted the number of doses to be decreased.
openaire +2 more sources
Mayo Clinic Proceedings, 1999
The cephalosporins are a large group of related beta-lactam antimicrobial agents. Favorable attributes of the cephalosporins include low rates of toxicity, relatively broad spectrum of activity, and ease of administration. Various cephalosporins are effective for treatment of many conditions, including pneumonia, skin and soft tissue infections ...
W F, Marshall, J E, Blair
openaire +2 more sources
The cephalosporins are a large group of related beta-lactam antimicrobial agents. Favorable attributes of the cephalosporins include low rates of toxicity, relatively broad spectrum of activity, and ease of administration. Various cephalosporins are effective for treatment of many conditions, including pneumonia, skin and soft tissue infections ...
W F, Marshall, J E, Blair
openaire +2 more sources
Immunology and Allergy Clinics of North America, 2004
Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
openaire +2 more sources
Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
openaire +2 more sources
Dual-action cephalosporins: cephalosporin 3'-quinolone carbamates
Journal of Medicinal Chemistry, 1991A series of cephalosporins has been prepared in which the 3'-position was linked to the nitrogen of the antibacterial quinolone ciprofloxacin through a carbamate function. Like the ester-linked and quaternary-linked dual-action cephalosporins reported earlier, these carbamate-linked compounds exhibited a broad antibacterial spectrum derived from both ...
H A, Albrecht +8 more
openaire +2 more sources
Journal of Medicinal Chemistry, 1977
The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
openaire +2 more sources
The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
openaire +2 more sources