Results 271 to 280 of about 137,963 (330)
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Cephalosporin resistance, tolerance, and approaches to improve their activities
Journal of antibiotics (Tokyo. 1968), 2023Alison H. Araten +8 more
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Clinics in Dermatology, 2003
O riginally developed based on research completed in the early 1940s by Professor Giuseppe Brotzu, the cephalosporins have sustained their position as a very significant class of antibiotics worldwide, comprising over one half of the available -lactam antibiotics.
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O riginally developed based on research completed in the early 1940s by Professor Giuseppe Brotzu, the cephalosporins have sustained their position as a very significant class of antibiotics worldwide, comprising over one half of the available -lactam antibiotics.
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Immunology and Allergy Clinics of North America, 2004
Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
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Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
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Continuous deacetylation of cephalosporins
Biotechnology and Bioengineering, 1980AbstractContinuous deacetylation of cephalosporin C, 7‐aminocephalosporanic acid, and of 2‐methoxyethyl acetate in packed beds of an immobilized esterase is described by simple empirical equations relating conversion to space velocity and temperature.
Jan, Konecny, M, Sieber
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Classification of Cephalosporins
Drugs, 1987Many cephalosporins are now in clinical use. They have a wide range of activity against different species of bacteria and also differ in their pharmacokinetic and metabolic characteristics. This article outlines a basis for comparison and classification of cephalosporins into 4 groups active mainly against: (1) Gram-positive bacteria; (2) Gram-negative
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Journal of Medicinal Chemistry, 1977
The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
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The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
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