Results 211 to 220 of about 40,632 (234)

The electrochemistry of cephalosporin C derivatives

Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1977
Abstract The electrochemical behavior of cephalothin has been studied by a.c. and d.c. polarography, cyclic voltammetry, and coulometry in both aqueous and nonaqueous media in order to gain a greater understanding of the reaction pathways involved in cephalosporin reduction.
Carol J. Schneider, David A. Hall, Donnis M. Berry   +2 more
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Fluidized bed adsorption of Cephalosporin C

Journal of Biotechnology, 2002
Fluidized bed adsorption can substantially simplify the recovery of products from fermentation. There are, however, several critical parameters, which have a significant influence on the performance of such systems. This paper presents experimental results on the adsorption of an antibiotic, Cephalosporin C, on macroporous adsorbents of the polystyrene
Klaus Buchholz, M Hicketier
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Methionine control of cephalosporin C formation

Biotechnology and Bioengineering, 1973
AbstractDL‐Norleucine, a nonsulfur analogue of methionine was found to markedly stimulate synthesis of cephalosporin C by Cephalosporium acremonium strain CW19 in three different chemically defined media. Methionine, but not norleucine, stimulated cephalosporin C biosynthesis in a crude medium.
Stephen W. Drew, Arnold L. Demain
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New Findings on Cephalosporin C Biosynthesis

Nature New Biology, 1973
IT has been reported that the fungus Cephalosporium sp. M8650 produces two peptide antibiotics, penicillin N and cephalosporin C, in the culture broth1–8. Three peptides which were presumed to be intermediates in the synthesis of β-lactam antibiotics have been isolated by Loder et al.9. Another group10 selected β-lactam antibiotic negative strains that
Shirafugi H, Toshihiko Kanzaki, Makoto Kida, Masahiko Yoneda, Kiyoshi Nara, Yukio Fujisawa   +5 more
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Destruction of Cephalosporin C by Ultraviolet Light [PDF]

Nature, 1966
WITH the recent development of potent penicillinase-resistant semi-synthetic cephalosporins1, there is considerable interest in the parent antibiotic, cephalosporin C (ref. 2). This antibiotic, which displays a peak of ultra-violet absorption at 260 mµ, is often detected on paper chromatograms by exposure to a source of ultraviolet light.
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Cephalosporin sulphoxides: functionalization at C-2 and C-4

Journal of the Chemical Society, Chemical Communications, 1976
AbstractDas (S)‐1‐Oxid (I) reagiert mit Acrylnitril in Gegenwart von Triäthylamin zum Addukt (II), dessen Um= ′ Setzung mit PBr3, gefolgt von einer Verseifung mit Zn/AcOH in DMF die Carbonsäure (III) ergibt.
David H. Bremner, Malcolm M. Campbell
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Studies on the cephalosporin C biosynthesis by fermentation

Archives of Pharmacal Research, 1979
UsingCephalosporium acremonium ATCC 14553, we studied on the important factors in fermentation. Those factors were: carbon and nitrogen sources, methionine effect, adsorbent effect, fermentation variables in a batch fermentation, effect of reuse of its cellular biomass as a reusable nutrient, and 2,4-dinitrophenol effect on cephalosporin C production.
Kang Man Lee, Dewey Doo-Young Ryu
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Monitoring of cephalosporin C during bioconversion

Applied Biochemistry and Biotechnology, 1996
A simple method based on Schiff’s base formation betweenp-dimethylaminobenzaldehyde and cephalosporin C is developed for estimation of cephalosporin C. The calibration curve was linear up to 500 μg of cephalosporin C. The application of the method in monitoring bioconversion of cephalosporin C to glutaryl-7-amino cephalosporanic acid is described.
Sudha S. Ambedkar, Bhagwant S. Despande, Jaiprakash G. Shewale   +2 more
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Cephalosporin C production in a stirred tank reactor

Applied Microbiology and Biotechnology, 1988
Cephalosporin C was produced with the moldCephalosporium acremonium in a 20 1 stirred tank reactor with 100 kg/m3 peanut flour in fed-batch operation. The growth and product formation was followed by on-line analysis of the broth composition. The cell concentration was estimated from the RNA-content of the cells.
T. Bayer, Karl Schügerl, T. Herold
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Extraction of cephalosporin C from whole broth and separation of desacetyl cephalosporin C by aqueous two‐phase partition

Biotechnology and Bioengineering, 1994
AbstractCephalosporin C was extracted from diluted or whole broth by PEG/salt aqueous two‐phase systems. Parameters such as PEG molecular weight, salt type, pH, and salt concentration were investigated for finding a suitable extraction system. In PEG 600/ammonium sulfate or phosphate systems, Kc (partition coefficienct of cephalosporin C) was observed ...
Chun‐Der Lin, Chau-Jen Lee, Wu‐Yung Yang, I-Ming Chu   +3 more
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