Results 41 to 50 of about 85,074 (245)

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Erythropoietic potential of Parquetina nigrescens in cephalosporin-induced anaemia model

Metabolism Open, 2020
Parquetina nigrescens is a folklore plant in Africa, particularly Nigeria, where its consumption is believed to stimulate red blood cells production. On this basis, the erythropoietic potential of the plant was evaluated in Cephalosporin-induced anaemia ...
O.M. Ighodaro, F.O. Asejeje, A.M. Adeosun, T.S. Ujomu, F.C. Adesina, K.T. Bolaji   +5 more
doaj   +1 more source

Estimating the number of infections caused by antibiotic-resistant Escherichia coli and Klebsiella pneumoniae in 2014: a modelling study [PDF]

, 2018
Background: The number of infections caused by resistant organisms is largely unknown. We estimated the number of infections worldwide that are caused by the WHO priority pathogens third-generation cephalosporin-resistant and carbapenem-resistant ...
Almagor, Jonatan, Carmeli, Yehuda, Fallach, Noga, Gladstone, Beryl Primrose, Tacconelli, Evelina, Temkin, Elizabeth   +5 more
core   +1 more source

Emerg. Infect. Dis [PDF]

, 2008
The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase(Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during 2000–2005.
Achtman, M., Delaune, A., Demartin, M., Egorova, S., Espie, E., Fabre, L., Granier, S., Grimont, P., Millemann, Y., Pardos, M., Sangal, V., Timinouni, M., Weill, F., Whichard, J.   +13 more
core   +1 more source

Resistance decay in individuals after antibiotic exposure in primary care: A systematic review and meta-analysis [PDF]

, 2012
Background Antibiotic resistance is an urgent global problem, but reversibility is poorly understood. We examined the development and decay of bacterial resistance in community patients after antibiotic use.
Bakhit, Mina, Hoffmann, Tammy, Scott, Anna Mae, Beller, Elaine, Rathbone, John, Del Mar, Chris   +5 more
core   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Beiträge zur Chemie der β-Lactam-Antibiotika

CHIMIA, 1976
A reaction sequence for the preparation of 7-Amino-3-alkoxyceph-3-em-4-carboxylic acids 4 from natural penicillins is outlined. Key steps involve an ozonolysis and a novel type of cyclisation reaction (2 → 3).
J. Gosteli
doaj   +1 more source

Comparative Studies on Cephalosporin C biosynthesis by Aspergillus and Acremonium Species [PDF]

, 2016
Three species of Aspergillus (A. Niger, A. flavus, A. nidulans) and two species of Acremonium (A. furcatum and A. kiliense) were tested for their potential to biosynthesis of cephalosporin-C (CPC) in batch mode of cultivation before and after mutagenesis.
Aftab, A. (Arusa), Bilal, Z. (Zill-e-Huma), Siddique, I. (Iffat), Yousaf, A. (Adeela)   +3 more
core   +1 more source

Evaluation of the Coverage of 3 Antibiotic Regimens for Neonatal Sepsis in the Hospital Setting Across Asian Countries. [PDF]

, 2020
Importance: High levels of antimicrobial resistance in neonatal bloodstream isolates are being reported globally, including in Asia. Local hospital antibiogram data may include too few isolates to meaningfully examine the expected coverage of antibiotic ...
Agarwal, R, Bielicki, JA, Cromwell, DA, Heath, PT, Sharland, M, Turner, P, Walker, AS   +6 more
core   +3 more sources

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source