Results 91 to 100 of about 73,761 (291)

Maternal infection in the context of actively managed prelabor rupture of membranes at term: An observational study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess maternal infection following prelabor rupture of membranes (PROM) at term in a setting where active management is recommended, and to identify associated risk factors. Methods A retrospective cohort study was conducted including pregnant women admitted to a Portuguese tertiary care center where immediate induction of labor ...
Inês Martins, Inês Gomes Brou, Miguel Macedo, Luísa Pinto   +3 more
wiley   +1 more source

Exploring the Chemical Space of Cephalosporins Across Generations

Drugs and Drug Candidates
Background/Objectives: Cephalosporins represent one of the most important classes of β-lactam antibiotics, widely used in clinical practice due to their broad-spectrum activity and favorable safety profile.
Henrique de Aguiar Mello, Itamar Luís Gonçalves   +1 more
doaj   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis

Frontiers in Pharmacology
IntroductionChemotherapeutic agents, despite their toxicities, variability in individual response, and risk of drug-drug interactions, are essential in the treatment of gastrointestinal cancers.
Robert Siegel, Sophie Schlosser-Hupf, Martina Müller-Schilling, Samer A. Kharroubi, André Gessner, Nahed El-Najjar, Nahed El-Najjar   +6 more
doaj   +1 more source

Determination of Cephalosporins Using Electrophoretic Techniques [PDF]

, 2010
Kefalosporinok vizsgálata elektroforetikus technikákkalDetermination of cephalosporins using electrophoretic ...
Andrási, Melinda
core  

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

iMetaOmics, EarlyView.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos‐Pastén, Gastón Azziz, Rosalba Lagos, Julieta Orlando, Francisco P. Chávez, Andrés E. Marcoleta   +8 more
wiley   +1 more source

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis [PDF]

, 2016
We report two series of novel cephalosporins that are bactericidal to Mycobacterium tuberculosis alone of the pathogens tested, which only kill M. tuberculosis when its replication is halted by conditions resembling those believed to pertain in the host,
Ben Gold (1263453), Yan Ling (16696), Selin Somersan (2827676), Patrick Porubsky (591099), Julia Roberts (235507), Landys Lopez Quezada (2827664), Quyen Nguyen (1312230), Frank J. Schoenen (1514281), Elaine Ballinger (2827670), Jeffrey Aubé (1314141), Thulasi Warrier (1263474), Maneesh Pingle (724237), Véronique Dartois (1604731), Lester A. Mitscher (2264080), Steven Rogers (1576642), Paul Hanson (2827667), David Little (1263468), Matthew Zimmerman (2827673), Carl Nathan (182832), David Zhang (394226), Robert Smith (2450401)   +20 more
core   +4 more sources

A STUDY ON DRUG UTILIZATION PATTERN OF CEPHALOSPORINS IN GENERAL MEDICINE AND SURGICAL INPATIENT DEPARTMENT [PDF]

, 2018
Objective: Cephalosporins are a commonly used group of antibiotics in hospitals and healthcare facilities around the world. In the developed countries through the use of older cephalosporins is declining, that of the newer generations has increased.
Chandana G., Siddiq, Abubaker, Abubaker Siddiq, G., Chandana, Naveen V., V., Naveen   +5 more
core   +2 more sources

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source