Results 31 to 40 of about 110,179 (326)

Third Generation Cephalosporin Resistant Enterobacterales Infections in Hospitalized Horses and Donkeys: A Case–Case–Control Analysis

Antibiotics, 2021
In human medicine, infections caused by third-generation cephalosporin-resistant Enterobacterales (3GCRE) are associated with detrimental outcomes. In veterinary medicine, controlled epidemiological analyses are lacking.
Anat Shnaiderman-Torban, Dror Marchaim, Shiri Navon-Venezia, Ori Lubrani, Yossi Paitan, Haya Arielly, Amir Steinman   +6 more
doaj   +1 more source

Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000–2013

Journal of Infectious Diseases, 2016
Background. Treatment of Neisseria gonorrhoeae infection is empirical and based on population-wide susceptibilities. Increasing antimicrobial resistance underscores the potential importance of rapid diagnostic tests, including sequence-based tests, to ...
Y. Grad, S. Harris, R. Kirkcaldy, Anna G. Green, D. Marks, S. Bentley, D. Trees, M. Lipsitch   +7 more
semanticscholar   +1 more source

Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota

Angewandte Chemie, EarlyView.
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog, Keishi Ishida, Kirstin Scherlach, Xiuqiang Chen, Benjamin Bartels, Sarah P. Niehs, Bachar Cheaib, Gianni Panagiotou, Christian Hertweck   +8 more
wiley   +2 more sources

Comparison of the effectiveness of preventive systemic administration of antibiotics with topical use of decamethoxin during clean surgical interventions

Perioperative Medicine, 2019
Introduction. The lack of generally accepted standards of perioperative antimicrobial prophylaxis leads to the inadequate preventive use of antibiotics associated with development of microbial resistance, changes in the natural biota and sensitization of
Anastasiia Hlaholieva
doaj   +1 more source

Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins

Antimicrobial Agents and Chemotherapy, 2015
Mutation-dependent overproduction of intrinsic β-lactamase AmpC is considered the main cause of resistance of clinical strains of Pseudomonas aeruginosa to antipseudomonal penicillins and cephalosporins.
M. Berrazeg, K. Jeannot, V. Y. N. Enguéné, I. Broutin, S. Loeffert, Damien Fournier, P. Plésiat   +6 more
semanticscholar   +1 more source

Repurposing clinically approved cephalosporins for tuberculosis therapy

Scientific Reports, 2016
While modern cephalosporins developed for broad spectrum antibacterial activities have never been pursued for tuberculosis (TB) therapy, we identified first generation cephalosporins having clinically relevant inhibitory concentrations, both alone and in
S. Ramón-García, Rubén González del Río, Angel Santos Villarejo, G. Sweet, Fraser Cunningham, David Barros, Lluís Ballell, Alfonso Mendoza-Losana, Santiago Ferrer-Bazaga, C. Thompson   +9 more
semanticscholar   +1 more source

Synthesis and Preliminary Antimicrobial Activities of New Arylideneamino-1,3,4-thiadiazole-(thio/dithio)-acetamido Cephalosporanic Acids

Molecules, 2012
New derivatives of 7-aminocephalosporanic acid 1–8 were synthesized by acylation of the 7-amino group of the cephem nucleus with various arylidinimino-1,3,4-thiadiazole-thio(or dithio)-acetic acid intermediates 3a–d and 5a–d, respectively, so the acyl ...
Shakir Mahmood Alwan
doaj   +1 more source

Emergence of meningococci with reduced susceptibility to third-generation cephalosporins

Journal of Antimicrobial Chemotherapy, 2017
Objectives Reduced susceptibility to penicillin G in Neisseria meningitidis is mainly due to alterations in PBP2 encoded by the penA gene. However, this phenotype was not associated with reduced susceptibility to third-generation cephalosporins (C3Gs ...
A. Deghmane, E. Hong, M. Taha
semanticscholar   +1 more source

Prevalence, antimicrobial resistance, and staphylococcal toxin genes of blaTEM‐1a‐producing Staphylococcus aureus isolated from animals in Chongqing, China

Veterinary Medicine and Science, Volume 9, Issue 1, Page 513-522, January 2023., 2023
The average isolation rate of livestock‐associated S. aureus is 6.5%, and the S. aureus isolates showed high resistance to a wide range of antimicrobials. Most strains, with the exception of three chicken‐associated strains, harbored blaTEM‐1a gene. All S.
Qingshuang Dong, Qing Wang, Yun Zhang, Yao Chen, Haoju Wang, Honglei Ding   +5 more
wiley   +1 more source

Role of cephalosporins in the era of Clostridium difficile infection

Journal of Antimicrobial Chemotherapy, 2016
The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since 2000. Previous meta-analyses have suggested a strong association between cephalosporin use and CDI, and many national programmes on CDI control have focused on ...
M. Wilcox, J. Chalmers, C. Nord, J. Freeman, E. Bouza   +4 more
semanticscholar   +1 more source