Results 241 to 250 of about 67,708 (303)

Glycolipid transfer protein modulates vesicular trafficking from the endoplasmic reticulum in HeLa cells. [PDF]

J Biol Chem
Nurmi H, Englund L, Henriksson A, Lönnfors M, Mattjus P.   +4 more
europepmc   +1 more source

Ceramide in gluco-lipotoxicity: possible impairment of ceramide flowing in complex sphingolipid biosynthesis in beta pancreatic cells

, 2011
H. Le Stunff, P. Viani, E. Gjoni, L.P.C.G. Riboni, J. Veret, P.C. Giussani   +5 more
core  

Cell Membrane Vesicles Encapsulating Il24 mRNA With Enriched CD6 Display Exhibit Enhanced Targeted Antitumor Efficacy

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT mRNA‐based therapeutics offer significant potential for cancer treatment owing to their ability to induce transient, non‐integrating expression of therapeutic proteins. However, effective and tumour‐specific delivery remains a major barrier.
Dandan Wang, Ruofan Gao, Duo Liu, Kefan Li, Runkai Wang, Minghe Xu, Shiwei Zhang, Shengjie Jiang, Bin Xia   +8 more
wiley   +1 more source

Hesperidin alleviates systemic inflammation and oxidative stress by remodeling adipose tissue lipid metabolism in periparturient dairy cows. [PDF]

J Anim Sci Biotechnol
Tan J, Wang Y, Niu H, Fang L, Zhao Y, Jiang L.   +5 more
europepmc   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan, Jiang Jiang, Shuangshuang Tu, Chuanfu Li, Yijun Dong, Yongjin Li, Wenzhi Zhang, Xi Chen   +7 more
wiley   +1 more source

S1P in Tumor Microenvironment and Modulation of Anti-Tumor-Directed T-Cell Responses. [PDF]

Cells
António PA, Lérias JR, Gorgulho CM, Balan K, Balan V, Maeurer MJ.   +5 more
europepmc   +1 more source

Listening to Cellular Whispers through Glycosphingolipids: A Comprehensive Review of Recent Advancements in Glycosphingolipid Analysis and Annotation. [PDF]

Anal Chem
Beirami AD, Rampler E.
europepmc   +1 more source

Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and composition. [PDF]

J Biol Chem
Nobumoto W, Naganuma T, Nozaka N, Ohno Y, Nojiri K, Kihara A.   +5 more
europepmc   +1 more source

Inhibition of de novo ceramide synthesis mitigates alpha-synuclein pathology in a Parkinson's disease mouse model. [PDF]

NPJ Parkinsons Dis
Lee E, Park MY, Park M, Kim NY, Wei S, Hwang N, Ryu D, Ryu H, Park D, Lee G, Oh CM.   +10 more
europepmc   +1 more source

Sphingolipidomic Profiling of Peripheral Blood Mononuclear Cells Reveals a Distinct Immunometabolic Signature Across Patients with Essential Obesity and Metabolic Syndrome Compared to Normal-Weight Healthy Subjects. [PDF]

J Clin Med
Rigamonti AE, Dei Cas M, Signorelli P, Bondesan A, Caroli D, Cella SG, Sartorio A.   +6 more
europepmc   +1 more source