Results 11 to 20 of about 55,413 (307)

Cerebellar cognitive disorder parallels cerebellar motor symptoms in Friedreich ataxia

Annals of Clinical and Translational Neurology, 2020
Dentate nuclei (DN) are involved in cerebellar modulation of motor and cognitive functions, whose impairment causes ataxia and cerebellar cognitive affective syndrome (CCAS).
Gilles Naeije, Myriam Rai, Nick Allaerts, Martin Sjogard, Xavier De Tiège, Massimo Pandolfo   +5 more
doaj   +2 more sources

Population-based study of acquired cerebellar ataxia in Al-Kharga district, New Valley, Egypt

Neuropsychiatric Disease and Treatment, 2011
Wafaa MA Farghaly1, Hamdy N El-Tallawy1, Ghaydaa A Shehata1, Tarek A Rageh1, Nabil Abdel Hakeem2, Noha M Abo-Elfetoh11Department of Neurology and Psychiatry, Assiut University, Assiut, Egypt; 2Al Azhar University, Assiut Branch, EgyptBackground: The aim ...
Farghaly WMA, El-Tallawy HN, Shehata GA, Rageh TA, Abdel Hakeem N, Abo-Elfetoh NM   +5 more
doaj   +3 more sources

Acute Cerebellar Ataxia Associated with Modest Elevation of Anti-GAD Antibodies in a Young Patient

Tremor and Other Hyperkinetic Movements, 2019
Background: Anti-GAD-related cerebellar ataxia has rarely been described as an acute cause of autoimmune ataxia. Phenomenology Shown: A young female who acutely developed anti-GAD-associated ataxia with magnetic resonance imaging (MRI) showing ...
Juliana Gomez, Dongkwan Jin
doaj   +1 more source

The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice [PDF]

, 2009
Ataxia represents a pathological coordination failure that often involves functional disturbances in cerebellar circuits. Purkinje cells (PCs) characterize the only output neurons of the cerebellar cortex and critically participate in regulating motor ...
Kneussel Matthias, Loebrich, S, Sven Loebrich, Hevers, Wulf, Michaela Schweizer, Eilers, Jens, Đikić, Ivan, Corinna Lappe-Siefke, Wilson, Scott M., Scott M Wilson, Waidmann Oliver B., Fehr Susanne, Schweizer, M, Kneussel, Matthias, Oliver B Waidmann, Fritschy Jean-Marc, Jean-Marc Fritschy, Wilson, S M, Schweizer Michaela, Jens Eilers, Eilers, J, Fritschy, Jean-Marc, Ivan Dikic, Fritschy, J M, Dikic, I, Schweizer, Michaela, Eilers Jens, Susanne Fehr, Waidmann, O B, Wilson Scott M., Fehr, Susanne, Matthias Kneussel, Fehr, S, Lappe-Siefke, Corinna, Waidmann, Oliver, Dikic Ivan, Loebrich Sven, Hevers Wulf, Lappe-Siefke, C, Hevers, W, Kneussel, M, Löbrich, Sven, Wulf Hevers, Lappe-Siefke Corinna   +43 more
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Severity and Progression Rate of Cerebellar Ataxia in 16q-linked Autosomal Dominant Cerebellar Ataxia (16q-ADCA) in the Endemic Nagano Area of Japan [PDF]

, 2009
16q22.1-linked autosomal dominant cerebellar ataxia (16q-ADCA) is a recently defined subtype of ADCA identified by a disease-specific C/T substitution in the 5' untranslated region of the puratrophin-1 gene. In Nagano, the central mountainous district of
Sato, Shunichi, Shimizu, Yusaku, Sakai, Haruya, Okano, Tomomi, Ikeda, Shu-ichi, Hattori, Takeshi, Ohara, Shinji, Tabata, Kenichi, Matsumoto, Naomichi, Inoue, Atsushi, Morita, Hiroshi, Ushiyama, Masao, Nakamura, Katsuya, Tazawa, Ko-ichi, Shimojima, Yasuhiro, Yoshida, Kunihiro, Ohata, Takako   +16 more
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Clinical spectrum of early onset cerebellar ataxia with retained tendon reflexes: an autosomal recessive ataxia not to be missed

Arquivos de Neuro-Psiquiatria, 2013
Autosomal recessive cerebellar ataxias are a heterogeneous group of neurological disorders. In 1981, a neurological entity comprised by early onset progressive cerebellar ataxia, dysarthria, pyramidal weakness of the limbs and retained or increased upper
Jose Luiz Pedroso, Pedro Braga-Neto, Irapua Ferreira Ricarte, Marcus Vinicius Cristino Albuquerque, Orlando Graziani Povoas Barsottini   +4 more
doaj   +1 more source

Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression

npj Regenerative Medicine, 2022
Peripheral nerve injury (PNI) often results in spontaneous motor recovery; however, how disrupted cerebellar circuitry affects PNI-associated motor recovery is unknown.
Pallavi Asthana, Gajendra Kumar, Lukasz M. Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K. Wszolek, Chi Him Eddie Ma   +11 more
doaj   +1 more source

Spinocerebellar Ataxia Type 2 [PDF]

, 2012
1. Introduction: The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections.
Georg Auburger, Hans-Joachim Freund, Rodríguez-Labrada, Roberto, Auburger, Georg, Freund, Hans-Joachim, Velázquez-Pérez, Luis, Roberto Rodrguez-Labrada, Luis Velázquez-Pérez, Luis Velzquez-Prez, Roberto Rodríguez-Labrada   +9 more
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Inferior cerebellar hypoplasia resembling a Dandy-Walker-like malformation in purebred Eurasier dogs with familial non-progressive ataxia: a retrospective and prospective clinical cohort study. [PDF]

PLoS ONE, 2015
Cerebellar malformations can be inherited or caused by insults during cerebellar development. To date, only sporadic cases of cerebellar malformations have been reported in dogs, and the genetic background has remained obscure.
Filipa Bernardino, Kai Rentmeister, Martin J Schmidt, Andreas Bruehschwein, Kaspar Matiasek, Lara A Matiasek, Alexander Lauda, Heinz A Schoon, Andrea Fischer   +8 more
doaj   +1 more source

Familial hemiplegic migraine with cerebellar ataxia and paroxysmal psychosis [PDF]

, 1999
Familial hemiplegic migraine is a rare autosomal dominant disorder associated with stereotypic neurologic au ra phenomena including hemiparesis, So far two chromosomal loci have been identified. Families linked to the chromosome 19 locus display missense
Spranger, S., Benninger, C., Schwab, S., Spranger, Matthias, Dichgans, Martin   +4 more
core   +1 more source