Results 21 to 30 of about 55,413 (307)

Cerebellar Transcranial Magnetic Stimulation Improves Ataxia in Minamata Disease

Case Reports in Neurology, 2019
Minamata disease (MD) is a form of intoxication involving the central nervous system and is caused by ingesting seafood from methylmercury-contaminated areas in Japan.
Masaaki Nakamura, Masafumi Bekki, Youko Miura, Mina Itatani, Liu Xiao Jie   +4 more
doaj   +1 more source

A Small Trinucleotide Expansion in the TBP Gene Gives Rise to a Sporadic Case of SCA17 with Abnormal Putaminal Findings on MRI [PDF]

, 2008
A Japanese woman developed gait disturbances at 25 years of age, and subsequently underwent gradual changes in her personality. By the age of 42, she showed clear signs of dementia and cerebellar ataxia, and displayed behavioral abnormalities, choreic ...
Suzuki, Chieko, Tomiyama, Masahiko, Jackson, Mandy, Ikeda, Yoshio, Yamamoto-Watanabe, Yukiko, Watanabe, Mitsunori, Kawarabayashi, Takeshi, Shoji, Mikio, Wakasaya, Yasuhito, Monai, Natsuki, Kimura, Tamaki, Miki, Yasuo, Matsubara, Etsuro, Seino, Yusuke   +13 more
core   +1 more source

Genetic and clinical features of cerebellar ataxia with RFC1 biallelic repeat expansions in Japan

Frontiers in Neurology, 2022
The recessive intronic pentanucleotide repeat AAGGG expansion of replication factor complex subunit 1 (RFC1) is associated with cerebellar ataxia, sensory neuropathy, and vestibular areflexia syndrome.
Masahiro Ando, Yujiro Higuchi, Junhui H. Yuan, Akiko Yoshimura, Shuntaro Higashi, Mika Takeuchi, Takahiro Hobara, Fumikazu Kojima, Yutaka Noguchi, Jun Takei, Yu Hiramatsu, Satoshi Nozuma, Yusuke Sakiyama, Akihiro Hashiguchi, Eiji Matsuura, Yuji Okamoto, Yuji Okamoto, Masahiro Nagai, Hiroshi Takashima   +18 more
doaj   +1 more source

The underpinnings of cerebellar ataxias

Clinical Neurophysiology Practice, 2022
The human cerebellum contains more than 60% of all neurons of the brain. Anatomically, the cerebellum is divided into 10 lobules (I-X). The cerebellar cortex is arranged into three layers: the molecular layer (external), the Purkinje cell layer and the granular layer (internal). Purkinje neurons and interneurons are inhibitory, except for granule cells.
openaire   +3 more sources

Idiopathic very late-onset cerebellar ataxia: a Brazilian case series

Arquivos de Neuro-Psiquiatria, 2015
The authors present a Brazilian case series of eight patients with idiopathic very-late onset (mean 75.5 years old) cerebellar ataxia, featuring predominantly gait ataxia, associated with cerebellar atrophy.Method: 26 adult patients with a diagnosis of ...
Hélio A. G. Teive, Mariana Moscovich, Adriana Moro, Marina Farah, Walter O. Arruda, Renato P. Munhoz   +5 more
doaj   +1 more source

Is Ataxia an Underestimated Symptom of Huntington's Disease?

Frontiers in Neurology, 2020
Background: Huntington's disease (HD) is a progressive disorder characterized by motor, cognitive and psychiatric features. Cerebellar ataxia is classically considered as uncommon in HD clinical spectrum.Objective: To determine the prevalence of ...
Gustavo L. Franklin, Carlos Henrique F. Camargo, Alex T. Meira, Giovana M. Pavanelli, Sibele S. Milano, Francisco B. Germiniani, Nayra S. C. Lima, Salmo Raskin, Orlando Graziani Povoas Barsottini, José Luiz Pedroso, Fernanda Aparecida Maggi, Vitor Tumas, Pedro Manzke de Carvalho, Ana Carolina de Oliveira, Bárbara Braga, Laura Cristina Souza, Rachel Paes Guimarães, Luiza Gonzaga Piovesana, Íscia Teresinha Lopes-Cendes, Paula Christina de Azevedo, Marcondes Cavalcante França, Alberto Rolim Muro Martinez, Hélio A. G. Teive   +22 more
doaj   +1 more source

Ataxia-telangiectasia mutated plays an important role in cerebellar integrity and functionality

Neural Regeneration Research, 2023
Accumulating evidence indicates that ataxia-telangiectasia mutated kinase is critical for maintaining cellular homeostasis and that it has both nuclear and cytoplasmic functions. However, the functions of ataxia-telangiectasia mutated that when lost lead
Yulia Mitiagin, Ari Barzilai
doaj   +1 more source

Variability in the Results of Vestibular Assessment in Patients with Genetically Confirmed Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome

, 2023
20.500.12530/87912BACKGROUND: Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS) presents an unpredictable and uneven clinical development of cerebellar ataxia, neuropathy, and vestibular areflexia.
Alfredo García-Fernández, Vergas-Gutiérrez, Joaquín Jesús De, María Fernandez-Rueda, Fernandez-Rueda, Maria, Jesus De Vergas-Gutierrez, Joaquin, Joaquín Jesús De Vergas-Gutiérrez, Garcia-Fernandez, Alfredo   +6 more
core   +1 more source

Progressive Supranuclear Palsy with Predominant Cerebellar Ataxia [PDF]

Journal of Movement Disorders, 2020
Progressive supranuclear palsy (PSP) is characterized by supranuclear gaze palsy, dystonic rigidity of the neck and upper trunk, frequent falls and mild cognitive impairment.
Shoichiro Ando, Masato Kanazawa, Osamu Onodera   +2 more
doaj   +1 more source

Childhood Cerebellar Ataxia [PDF]

Journal of Child Neurology, 2012
Childhood presentations of ataxia, an impairment of balance and coordination caused by damage to or dysfunction of the cerebellum, can often be challenging to diagnose. Presentations tend to be clinically heterogeneous, but key considerations may vary based on the child’s age at onset, the course of illness, and subtle differences in phenotype ...
openaire   +2 more sources